Heat-sensitive gel containing matrine alkaloid and its preparing method
A sensitive gel and matrine technology, applied in the field of heat-sensitive gels, can solve the problems of difficult gel viscosity control, unfavorable dispersion of affected parts, outflow, etc., achieve good heat-sensitive gel properties and prolong residence time , easy to clean effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0025] Example 1 Single-dose packaged thermosensitive gel for vagina (specification 2g / bottle, 1000 pieces)
[0026] Prescription: Component name Dosage (g)
[0027] Matrine 50
[0028] Hypromellose 17.46
[0029] Poloxamer 407 362
[0030] pH5.0 Phosphate Buffer 1368
[0031] Glycerin 200
[0032] Sorbic acid 2
[0033] Methylparaben 2
[0034] According to the prescription, each component is weighed, and matrine is added into the pH5.0 phosphate buffer solution, and stirred to dissolve. Add hypromellose to the obtained solution to dissolve, then add poloxamer 407 to stir and dissolve, and finally add sorbic acid, methyl p-hydroxybenzoate and glycerin to dissolve. Each unit preparation is 2g, divided into disposable vaginal injectors, plus outer packaging. Injected into the vagina when used.
Embodiment 2
[0035] The heat-sensitive gel for external genital mucous membrane of embodiment 2 multi-dose packaging (specification 5g / supports, 1000)
[0036] Prescription: Component name Dosage (g)
[0037] Oxymatrine 125
[0038] Hypromellose 45
[0039] Poloxamer 407 950
[0040] pH6.0 Phosphate Buffer 3320
[0041] Glycerin 550
[0042] Sorbic acid 10
[0043] According to the prescription, weigh each component, add oxymatrine into pH6.0 phosphate buffer solution, and stir to dissolve. Add hypromellose to the obtained solution to dissolve, then add poloxamer 407 to stir and dissolve, and finally add sorbic acid and glycerin to dissolve. 5 g per unit formulation, dispensed into spray bottles. Press and spray the affected area when using.
Embodiment 3
[0044] The thermosensitive gel for the vagina of embodiment 3 single-dose packaging (specification 5g / support, 1000)
[0045] Prescription: Component name Dosage (g)
[0046] Oxymatrine 100
[0047] Hypromellose 45
[0048] Poloxamer 407 900
[0049] pH5.5 Phosphate Buffer 3545
[0050] Glycerin 400
[0051] Sorbic acid 10
[0052] According to the prescription, weigh each component, add oxymatrine into pH5.5 phosphate buffer solution, and stir to dissolve. Add hypromellose to the obtained solution to dissolve, then add poloxamer 407 to stir and dissolve, and finally add sorbic acid and glycerin to dissolve. Each unit preparation is 5g, divided into disposable vaginal injectors, plus outer packaging. Injected into the vagina when used.
PUM
Property | Measurement | Unit |
---|---|---|
Phase transition temperature | aaaaa | aaaaa |
Phase transition temperature | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com