Medicament for treating cerebral infarction and preparation method thereof

A technology for cerebral infarction and drugs, which can be used in drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as poor treatment effect, and achieve good treatment effect.

Active Publication Date: 2011-01-26
QIANFOSHAN HOSPITAL OF SHANDONG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These medicines in the prior art are mostly based on nourishing qi and activating blood circulation, ignoring the pathogenesis evolution that

Method used

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  • Medicament for treating cerebral infarction and preparation method thereof
  • Medicament for treating cerebral infarction and preparation method thereof
  • Medicament for treating cerebral infarction and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Example 1 Preparation of a drug for treating cerebral infarction

[0037] The formula is: Salvia 300g, Astragalus 400g, Leech 100g, Earthworm 200g, Angelica 200g, Sanqi 60g, Drynaria 200g, Coptidis 120g, Rhizoma Chuanxiong 200g.

[0038] The preparation method is:

[0039] (1) Crush notoginseng into fine powder, set aside;

[0040] (2) Take astragalus, salvia miltiorrhiza, chuanxiong, coptis, earthworm, leech, angelica and rhizoma drynaria, mix them, add 6 times the amount of 70% ethanol solution (by weight) to extract for 1 hour, filter to obtain the filtrate and medicinal residues, and the filtrate is used after recovering ethanol;

[0041] (3) Add 8 times the amount of water (in multiples by weight) to the medicinal dregs, decoct and extract for 1 hour, filter to obtain the filtrate, and reclaim the ethanol from the filtrate for subsequent use;

[0042] (4) Combine the filtrates obtained in steps (2) and (3), concentrate under reduced pressure to a thick paste wit...

Embodiment 2

[0043] Example 2 Preparation of a drug for the treatment of cerebral infarction

[0044] The formula is: Salvia 280g, Astragalus 420g, Leech 80g, Earthworm 220g, Angelica 170g, Sanqi 80g, Drynaria 170g, Coptidis 150g, Rhizoma Chuanxiong 170g.

[0045] The preparation method is:

[0046] (1) Crush notoginseng into fine powder, set aside;

[0047] (2) Take astragalus, salvia miltiorrhiza, chuanxiong, coptis, earthworm, leech, angelica and rhizoma drynaria, mix them, add 3 times the amount of 95% ethanol solution (by weight) to extract for 0.5 hours, filter to obtain the filtrate and medicinal residues, and the filtrate is used after recovering ethanol;

[0048] (3) Add 3 times the amount of water (by weight) to the dregs, decoct and extract for 0.5 hour, filter to obtain the filtrate, and reclaim the ethanol from the filtrate for subsequent use;

[0049] (4) Combine the filtrates obtained in steps (2) and (3), concentrate under reduced pressure to a thick paste with a relativ...

Embodiment 3

[0050] Example 3 Preparation of a drug for the treatment of cerebral infarction

[0051] The formula is: Salvia 320g, Astragalus 380g, Leech 120g, Earthworm 170g, Angelica 220g, Panax notoginseng 50g, Drynaria 220g, Coptidis 80g, Rhizoma Chuanxiong 220g.

[0052] The preparation method is:

[0053] (1) Crush notoginseng into fine powder, set aside;

[0054] (2) Take astragalus, salvia miltiorrhiza, chuanxiong, coptis, earthworm, leech, angelica and rhizoma drynaria, mix them, add 10 times the amount of 1% ethanol solution (by weight) to extract for 3 hours, filter to obtain the filtrate and medicinal residues, and the filtrate is used after recovering ethanol;

[0055] (3) Add 10 times the amount of water (in multiples by weight) to the medicinal dregs, decoct and extract for 3 hours, filter to obtain the filtrate, and reclaim the ethanol from the filtrate for subsequent use;

[0056] (4) Combine the filtrates obtained in steps (2) and (3), concentrate under reduced pressur...

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PUM

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Abstract

The invention discloses a medicament for treating cerebral infarction, which is prepared from the following raw material medicaments in part by weight: 100 to 500 parts of root of red rooted salvia, 200 to 600 parts of astragalus, 1 to 300 parts of leech, 20 to 400 parts of earthworm, 20 to 400 parts of Chinese angelica, 1 to 260 parts of root of pseudo-ginseng, 20 to 400 parts of drynaria rhizome, 1 to 320 parts of coptis root and 20 to 400 parts of Szechuan lovage rhizome. The Chinese medicinal preparation has main functions of promoting blood circulation and tonifying qi, dissolving stasis and dredging channels, and is used for qi deficiency and blood stasis symptoms of cerebral infarction such as hemiplegia, skew mouth and tongue, obscure words, hemiparesthesia, hard breathing, lacking in strength and the like.

Description

technical field [0001] The invention relates to a medicine for treating cerebral infarction and a preparation method thereof. Background technique [0002] Cerebral infarction (CI), also known as cerebral ischemic stroke (CIS), refers to softening and necrosis of local brain tissue due to blood circulation disturbance, ischemia and hypoxia. Cerebral infarction is mainly caused by atherosclerosis and thrombosis in the arteries supplying blood to the brain, narrowing or even occluding the lumen, resulting in focal acute cerebral insufficiency; Circulation into the cerebral arteries or the carotid arteries supplying cerebral blood circulation, resulting in blockage of blood flow or sudden decrease in blood flow, resulting in softening and necrosis of brain tissue in the corresponding innervated area. The former is called atherosclerotic thrombotic brain infarction (ABI), accounting for 40% to 60% of the disease, and the latter is called cerebral embolism (CE), accounting for 1...

Claims

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Application Information

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IPC IPC(8): A61K36/718A61P9/10A61K35/62A61K35/64
Inventor 李长生杨晓妮李凤玲薛琳
Owner QIANFOSHAN HOSPITAL OF SHANDONG
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