Method for constructing porosity-controlled bionic scaffold

Abstract

The invention relates to a method for constructing a porosity-controlled bionic scaffold, which comprises the following steps of: scanning the entire natural bone by using Micro-CT technology, extracting spongy bone data and reconstructing a porous structure model of a spongy bone; measuring the porosity of the spongy bone model by using Mimics; then constructing a unit body with a proper porous structure according to the porosity; processing the unit body by using an image to obtain a three-dimensional porous structure model; and finally, performing Boolean intersection operation on the three-dimensional porous structure model and a damaged bone model so as to construct a porous structure model of the bionic scaffold, which is matched with the damaged part. In the method, the porosity corresponding to the natural bone can be obtained in the process of reconstructing and measuring, the characteristics of the natural bone can be better simulated in construction, and cell adhesion, crawling and bone replacement are more convenient. The bone scaffold constructed by the method has the same outline as real bone, which better contributes to implantation of the scaffold. A parameterized construction method can adjust different porosity characteristics of different natural bones and makes scaffold construction convenient. A construction method for obtaining the unit body by processing a unit body image solves the problem of porosity communication in a microstructure.

Description

technical field [0001] The invention relates to a construction method of an artificial bone for orthopedic medical repair, in particular to a construction of a natural bone-based bionic support with controllable porosity. Background technique [0002] With the rapid development of material science and medical technology, as well as the improvement of people's living standards, medical care, and rehabilitation, coupled with the aging of the population, people have increasingly urgent requirements for the repair and replacement of human tissue, organ, and bone defects. It has always been a difficult problem for orthopedic surgeons to repair various bone defects caused by trauma, infection, tumor and other diseases, especially the large defects of the long bone backbone of the limbs. Bone transplantation is a conventional treatment method, but the source of autologous bone is limited, while allogeneic bone transplantation has the risk of immune rejection and disease transmissio...

AI Technical Summary

Problems solved by technology

However, in the reconstruction process, the microscopic pore structure of the artificially designed scaffold is still very different from the structure of natural real bone. The porosity and connectivity of the microscopic tissue cannot be controlled, and it is difficult to fully guarantee the functionality of its structure; and, Most of the traditional scaffold construction methods do not use parametric construction ideas, so the porosity of the bionic scaffold cannot be adjusted in time according to the patient's natural bone characteristics

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