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Medicament formula and preparation thereof for preventing and curing altitude reaction and coronary heart disease

A technology for altitude sickness and coronary heart disease, applied in the direction of medical formula, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of less coronary heart disease and angina pectoris, and achieve the effect of high-quality selection, rapid altitude sickness, and alleviation of altitude sickness

Inactive Publication Date: 2011-04-06
江春艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are very few drugs that can effectively treat altitude sickness and coronary heart disease angina pectoris at the same time.

Method used

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  • Medicament formula and preparation thereof for preventing and curing altitude reaction and coronary heart disease
  • Medicament formula and preparation thereof for preventing and curing altitude reaction and coronary heart disease
  • Medicament formula and preparation thereof for preventing and curing altitude reaction and coronary heart disease

Examples

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Effect test

example 1

[0006] Example 1 - Preparation of Dropping Pills

[0007] (1) Extraction and purification process and conditions of salidroside

[0008] Take the prescribed amount of Rhodiola rosea, crush the Rhodiola rosea medicinal material, and pass through a No. 1 sieve. Add 70% ethanol according to the ratio of solid to liquid 1:8, heat the electric heating mantle to reflux and extract 3 times, each time for 1 hour, filter with a 200-mesh filter cloth, combine the filtrates, and recover the ethanol until it has no alcohol smell. Centrifuge the extract (centrifugal force: 3200, 10 min), take an appropriate amount of the supernatant and load the sample, first elute with 1 times the column volume of water, then elute with 50ml / 1g of 10% ethanol of medicinal materials, collect the 10% ethanol eluate, Concentrate to dryness. Purified salidolin was obtained.

[0009] research content:

[0010] Weigh 20g of Rhodiola rosea coarse powder, add 70% ethanol, according to the material-to-liquid r...

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Abstract

The invention relates to a medicament formula and a preparation thereof for preventing and curing an altitude reaction and a coronary heart disease. The medicament formula comprises 10 to 40g of rhodiola rosea, 60 to 150g of salvia miltiorrhiza, 1 to 5g of ginkgo biloba extract and 0.3 to 1.5g of artificial musk or borneol. The preparation comprises oral solid preparations of dripping pills, troches, capsulas, granules, pills, powder, and the like. The preparation method of dripping pills is characterized by extracting salvianolic acid B of salvia miltiorrhiza extract by adopting a method combining alcohol extraction and ethyl acetate extraction, the purifying method adopts macroporous adsorbent resins, and an eluent is 20% to 60% ethanol. The extraction of salidroside of rhodiola rosea extract adopts 30 to 90% ethanol for heating and backflow, the purifying method adopts the macroporous adsorbent resins, and the eluent is 10 to 50% ethanol. A salvia miltiorrhiza purified matter (salvianolic acid B), a rhodiola rosea purified matter (high-purity salidroside), the ginkgo biloba extract and the artificial musk or borneol are mixed with PEG (polyethyleneglycol) 4000 and PEG 6000 which are 0.5-3 times the amount of the salvia miltiorrhiza purified matter (salvianolic acid B), the rhodiola rosea purified matter (high-purity salidroside), the ginkgo biloba extract and the artificial musk or borneol, the , the mixture is heated for fusion and kept at 60 to 80 DEG C, and the mixture is dropped to a coolant, condensated, screened and dried to obtain the preparation.

Description

Technical field [0001] The invention relates to a medicinal formula and preparation for preventing and treating altitude sickness and coronary heart disease. Background technique [0002] Altitude sickness is Acute High Altitude Disease (AHAD), which is a natural phenomenon that occurs when a person reaches a certain altitude and the body adapts to changes in air pressure, low oxygen content, and dry air caused by altitude. Physiological reaction, when the altitude generally reaches about 2700 meters, there will be altitude sickness. Altitude sickness is an important content of altitude medicine, and the germination of altitude medicine started from people's understanding of altitude sickness and the proposal of prevention and treatment. Altitude sickness is not only a huge threat to those who quickly enter the plateau and those who live in the plateau for a short time, but also a serious problem to those who have lived in the plateau for a long time and have lived in the p...

Claims

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Application Information

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IPC IPC(8): A61K36/537A61K9/20A61P9/10A61P39/00A61K31/045A61K31/122
Inventor 严冬
Owner 江春艳
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