Medicine carrying method of medical sponge

Abstract

The invention discloses a medicine carrying method of a medical sponge. In the method, a macromolecular compound with a medicine slow release or controlled release effect is used as a carrier for coating a medical compound with a therapeutic function, the holes of the medical sponge are used for adsorbing a mixed solution carrying medicines and the carrier, and simultaneously, a compound with a physical or chemical cross-linking effect on the carrier macromolecular compound is added to be dried and sterilized to obtain a medicine carrying medical sponge. The medicine carrying medical sponge prepared by the method can be cut into a proper size according to the size of an operation cavity to be put into a corresponding position, so that the ambient pressure is balanced, and the damage to the mucous membrane of the operation cavity is small. The medicine carrying medical sponge prepared by the method disclosed by the invention has good biocompatibility and adhesivity, has an active function of promoting wound healing, has a hemostatic effect and a better medicine slow release effect, can be combined with partial antibacterial medicines for treating infection, can relieve the pain and discomfort of a patient, can be possibly used for replacing imported products, and has obvious social and economic benefits.

Description

technical field [0001] The invention belongs to the field of medical biomaterials, in particular to a drug-loading method for medical sponges. Background technique [0002] Trauma and surgery shows a clear upward trend every year in the world. The American Medical Association (AMA) recently released a white paper to Congress and the public, exclaiming that the annual medical expenditure on trauma and surgery in the United States is 103.7 billion US dollars. Wound repair is one of the most important and fundamental issues facing surgery and the entire medical community. Traditional dressings (gauze) only play the role of simply covering the wound. With the rapid development of modern medicine, especially molecular biology, there is a higher demand for dressings, that is, dressings should not only cover wounds, but also have the function of promoting tissue repair, providing a growth environment for new tissues, and accelerating wound healing , reduces scarring, prevents ba...

AI Technical Summary

Problems solved by technology

[0005] Patent CN1095988A also provides a drug sponge and its preparation method. The invention patent is to make the drug to be added into powder or liquid, then mix it with the original sponge and ingredients, stir thoroughly, and then put it into the designed mold. Foaming and forming according to the normal foaming process, the added medicine may be lost during the cleaning and purification process of the sponge, or the efficacy of the medicine may change due to the influence of foaming agents, catalysts and other chemicals

Patent 200310121182.X mixes and stirs a certain proportion of chitosan acetic acid aqueous solution, polyvinyl alcohol and gelatin solution, and glycerin to prepare a chitosan gelatin polyvinyl alcohol biological hemostatic dressing. The porosity of the dressing prepared by this method is low and cannot For negative pressure drainage occasions

Patent No. 97101655.0 uses polyvinyl formal porous material as a carrier to combine antibacterial drugs and analgesic local anesthetic drugs by physical adsorption. Since the drug is only combined with the carrier in a physical way, if it is used for negative pressure drainage, the drug is easily removed from the Separation from the carrier will not have the desired curative effect