Micro solenoid radio frequency coil for microfluid nuclear magnetic resonance detection and manufacturing method thereof

Abstract

The invention relates to a micro solenoid radio frequency coil for microfluid nuclear magnetic resonance detection and a manufacturing method thereof. The micro solenoid radio frequency coil comprises a bottom slanted-bar coil, left and right rows of bottom coils, cylindrical coils, a microfluid passage and a top slanted-bar coil, wherein the bottom slanted-bar coil and the left and right rows ofbottom coils are positioned on an insulating substrate; the cylindrical coils are arranged on the top parts of the bottom coils; the mocrofluid passage is positioned between the left and right rows of bottom coils; the top slanted-bar coil is positioned above the microfluid passage; both ends of the bottom slanted-bar coil are respectively connected with the left and right rows of bottom coils ina staggered mode; both ends of the top slanted-bar coil are respectively connected with the cylindrical coils arranged on the top parts of the bottom coils in a staggered mode; and the inclination directions of the bottom slanted-bar coil and the top slanted-bar coil are opposite to each other. In the invention, the micro solenoid radio frequency coil is manufactured by a photoresist photoetchingtechnology and a copper electroplating coil technology; the defect that a micro-scale solenoid radio frequency coil is difficult to wind is overcome; and the micro solenoid radio frequency coil has the advantages of high uniformity of a radio frequency magnetic field and the like and can be used for nuclear magnetic resonance detection of rare and precious samples.

Description

technical field [0001] The invention relates to a radio frequency coil used for microfluid nuclear magnetic resonance detection, in particular to a radio frequency micro coil with a uniform magnetic field distribution of a solenoid and a manufacturing method thereof. Background technique [0002] NMR spectroscopy is non-destructive to samples and is therefore widely used in the fields of chemistry, biomedicine and materials science. The nuclear magnetic resonance radio frequency coil can use a separate transceiver or a coil with both transceivers. The transmitting function is used to transmit the pulse sequence to excite the magnetization vector of the measured sample, and the receiving function is used to receive the free induction attenuation generated by the excited spin. Signal. The Fourier transform of the signal can be used to obtain the nuclear magnetic resonance spectrum, and the information such as the composition of the measured sample can be obtained. According ...

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Problems solved by technology

[0004] What the present invention aims to solve is that the existing conventional microfluidic detection is not easy to be suitable for the detection of micro samples; the radio frequency magnetic field of the miniature planar helical coil is uneven and the sensitivity is low; the miniature solenoid coil is not easy to be manufactured by the conventional winding method; Magnetic field, Helmholtz-type (saddle) coil has a large resistance and reduces the signal-to-noise ratio, etc.

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