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New method for correcting flavor of traditional Chinese medicine granule

A kind of traditional Chinese medicine granules and new technology, which are applied in the directions of pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc., to achieve the effects of wide application, good taste and improved compliance.

Active Publication Date: 2011-06-29
SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Literature search shows that there is no relevant literature or patent report on this method in China at present.

Method used

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  • New method for correcting flavor of traditional Chinese medicine granule
  • New method for correcting flavor of traditional Chinese medicine granule
  • New method for correcting flavor of traditional Chinese medicine granule

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Example 1 Shuanghuanglian Flavor Granules

[0018] Prescription composition: forsythia, baicalin, honeysuckle

[0019] Each medicinal material prepared 9 kg of drug granules according to the process method of the 2005 edition of the Pharmacopoeia without adding any corrective agent. Packed into 3000 bags.

[0020] In addition, 200 g of menthol and 1 kg of cyclodextrin were taken for inclusion complexation, and 150 g of sweetener aspartame was taken, mixed evenly with the menthol inclusion complex, and dry granulated to obtain flavoring agent granules. Pack into filter cotton paper bags (the packaging does not react with the drug), 0.45g of particles per bag, and seal. A total of 3000 bags were prepared.

[0021] The filter cotton paper bag is individually packaged together with the drug granule packaging to ensure that the number of flavoring agent granule bags in the box is the same as the number of drug granule bags.

[0022] When using it, patients can directly t...

Embodiment 2

[0026] Example 2 Pediatric Ganmao Granules

[0027] Prescription composition: Patchouli, Forsythia, Chrysanthemum, Folium Isatidis, Rehmannia glutinosa, Digupi, Baiwei, Mint, Gypsum

[0028] Each medicinal material prepared 30 kg of drug granules according to the process method of the 2005 edition of the Pharmacopoeia, without adding any corrective agent. Packed into 2500 bags.

[0029] In addition, 150 g of sweetener stevioside and 200 g of microcrystalline cellulose were taken, mixed evenly, and centrifuged to make pellets to obtain flavoring agent pellets. Pack into non-woven paper bags (the packaging does not react with medicine), 0.14g of particles per bag, and seal. A total of 2500 bags were prepared.

[0030] The non-woven paper bag is individually packaged together with the drug granules, and each bag of granules contains a bag of flavoring agent.

[0031] When using it, patients can directly tear open the package of granules, pour out the granules and flavoring ag...

Embodiment 3

[0035] Example 3 Qinglin Granules

[0036] Prescription composition: Qumai, Akebia, Plantago Seed (stir-fried with salt), Talc, Gardenia, Rhubarb, Roasted Licorice

[0037] Each medicinal material prepared 10 kg of drug granules according to the process method of the 2005 edition of the Pharmacopoeia, without adding any corrective agent. Packed into 1000 bags.

[0038] In addition, 50 g of sweetener sodium saccharin, 20 g of monosodium glutamate, and 50 g of sodium carboxymethyl starch were taken, mixed evenly, and GLATTmini fluidized bed granulation to obtain flavoring agent granules. Pack into filter cotton paper bags (the packaging does not react with the drug), 0.12g of particles per bag, and seal. A total of 1000 bags were prepared.

[0039] The non-woven paper bag is individually packaged and boxed together with the granule package to ensure that the number of flavoring agent granule bags in the box is the same as the number of drug granule bags.

[0040] When using ...

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Abstract

The invention discloses a new method for correcting flavor of a traditional Chinese medicine granule, comprising the following steps: independently processing auxiliary materials for correcting the flavor; independently internally packaging to form an independently packaged flavoring agent; packaging together with the traditional Chinese medicine granule so that patients can select whether to use the flavoring agent or not. According the invention, the purposes of satisfying the requirements of different people can be finally met, and a greater right is given to patients for selection. The method is suitable for industrial production; and by utilizing the method, the different requirements of different people on the mouth feel of the medicament can be ensured, and the requirements of special people on the flavoring agent can be satisfied; and the traditional Chinese medicine granule subjected to flavor correction by the method provided by the invention has the advantages of good mouth feel and wide application range, and is especially beneficial for the old, the children, and the patients with diabetes to take.

Description

technical field [0001] The invention relates to a method for correcting the taste of traditional Chinese medicine preparations, in particular to a novel method for correcting the taste of traditional Chinese medicine granules. Background technique [0002] The taste of medicines can affect patients' compliance with taking medicines. For drugs with poor taste, flavoring agents are often added in the formulation development process to cover up the bad taste. And these correctives have no therapeutic effect for patients, and for special patients, there may also be some side effects. It is also found in clinical practice that some people have a strong tolerance for bad taste, and they think that they do not need the help of flavoring agents, and taking too much flavoring agents will increase the burden on the body. There are also some people who have a unique perception of taste. These people often cannot accept a certain taste, and even cause vomiting. This specific taste may...

Claims

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Application Information

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IPC IPC(8): A61K36/00A61K47/26A61K47/44A61K47/18A61K47/22A61K47/61A61K47/69
Inventor 王优杰冯怡阮克锋徐德生
Owner SHANGHAI UNIV OF T C M