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Medicine for treating urinary stones and hyperuricemia
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A technology for urinary system stones and hyperuricemia, applied in drug combinations, urinary system diseases, pharmaceutical formulations, etc., can solve problems such as inability to effectively eliminate, spread, and large toxic and side effects
Inactive Publication Date: 2012-10-17
盛骝吾
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Problems solved by technology
With the improvement of people's living standards, the incidence of urinary stones and hyperuricemia is increasing year by year, and the number of patients is increasing significantly, and it is spreading to younger age groups. Currently, the conventional methods for treating urinary stones include surgical removal and drug exclusion. Among them, the drug elimination method has no special drug effect, and traditional Chinese medicine is mostly used for recuperation. This kind of traditional Chinese medicine has a certain effect on relieving urinary tract stones, but it cannot effectively rule out urinary tract stones.
For the treatment of hyperuricemia, "allopurinol" and "colchicine" are usually used. Although these drugs have certain curative effects, they have great toxic and side effects on the human body. Among them, "colchicine" has been banned by the Ministry of Health.
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Embodiment 1
[0025] Embodiment 1 (granular medicine):
[0026] The powder-painted medicine for treating calculus and hyperuricemia, its raw material components and molar ratio are: dipotassium citrate 1: disodium citrate 0.69: sodiumcarbonate 0.31: food coloring (appropriate amount): food essence (appropriate amount), they All belong to the excellent products of the pharmaceutical industry.
[0027] The preparation method of the above-mentioned medicine is as follows: select medical excellent grade dipotassium citrate, disodium citrate and sodium carbonate according to the molar ratio, add appropriate amount of water (refer to the solubility of sodium carbonate and add water). Put the above raw materials into the mixer, stir and mix well to cool down, evaporate the water, and then send it to the dryer to ensure that the temperature is 104 ° C ~ 110 ° C, and the drying time is 1 hour and 30 minutes to ensure that the main content reaches 99.5%. For the best, it can be packaged and sealed ...
Embodiment 2
[0037] Embodiment 2 (water dosage form medicament)
[0038] If dispensing 10% aqueous medicament, by weight, get 10 kilograms of granular medicine of the present invention, dissolve with 100 kilograms of pure water, heat and catch carbon dioxide, cool, pack.
[0042] That is, the product composition is: K + :Na + :H + l ≡ =1:1:0.54:0.85 (molar ratio).
[0043] L ≡ : Citric acid root. C 1 =[H 3 L], C 2 =[H 2 L - ], C 3 =[HL ＝ ]
[0044] Ka 1 =7.4·10 -4 , Ka 2 =1.7·10 -5 , Ka 3 =4·10 -7 .
[0045] The relationship between the distribution coefficient and the pH value of various forms in the citric acid solution is calculated by the following formula:...
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Abstract
The invention discloses a medicine for treating urinary stones and hyperuricemia and a preparation method thereof. The preparation method prepares the granular medicine by using potassium citrate dihydrogen, sodium hydrogencitrate and sodiumcarbonate as main raw materials and adding proper additives such as pigments, essences and the like, and by the steps of mixing the raw materials according to a certain ratio requirement, stirring, drying, evaporating, weighing, packaging and the like. In the invention, the formula and preparation method of the medicine are unique, and the treatment effect of the medicine is remarkable. The medicine disclosed by the invention also can regulate extracorporeal shock-wave lithotripsy (ESWL), enhance effect of lithotripsy and promote the dissolution and excretion of residual stones.
Description
Technical field: [0001] The invention relates to a medicine for treating urinary calculi and hyperuricemia and a preparation method thereof. Background technique: [0002] Hyperuricemia and its complications, and urinary calculi are common and frequently-occurring diseases that seriously endanger human health. Complications of hyperuricemia include uric acid renal failure, arteriosclerosis, and hypertension. With the improvement of people's living standards, the incidence of urinary stones and hyperuricemia is increasing year by year, and the number of patients is increasing significantly, and it is spreading to younger age groups. Currently, the conventional methods for treating urinary stones include surgical removal and drug exclusion. Among them, the drugelimination method has no special drug effect, and traditional Chinese medicine is mostly used for recuperation. This type of traditional Chinese medicine has a certain relieving effect on urinary calculi, but it canno...
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Application Information
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