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Preparation method of Mount Taishan cordycep medical base fermented antitussive agent

A technology of Cordyceps and fermenter, which is applied in the direction of medical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as human harm, toxic and side effects, and achieve growth promotion, good safety, and high medicinal value. Effect

Inactive Publication Date: 2011-11-09
聂心语 +1
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  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] There are many types of antitussive drugs on the market, but all of them have more or less toxic side effects, and long-term use will cause certain harm to the human body

Method used

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  • Preparation method of Mount Taishan cordycep medical base fermented antitussive agent

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preparation example Construction

[0022] A preparation method of a Taishan Cordyceps medicine-based fermented antitussive agent, firstly prepare a medium: use the following raw materials in parts by mass: 1000 parts of distilled water, 200 parts of potatoes, 20 parts of glucose, 5 parts of peptone, and 2 parts of potassium dihydrogen phosphate , 2 parts of magnesium sulfate.

[0023] Extraction of apricot leaf ginseng: 100g of apricot leaf ginseng powder, 1000ml of distilled water, decocting until boiling and then keeping a slight boil for 30min, taking the supernatant and concentrating it to 100ml under reduced pressure to obtain the apricot leaf ginseng extract.

Embodiment 1

[0025] (1) Medicinal-based fermentation: add 2% apricot leaf ginseng extract to the above basic medium, insert the Cordyceps taishan strain into the fermenter, shake and ferment at 140r / min, room temperature 20°C for 72h;

[0026] (2) Separation and extraction: Heat the above-mentioned drug-based fermentation product in a water bath at 50°C for 50 minutes, break the wall, take the supernatant, and concentrate to 1 / 6 of the original volume;

[0027] (3) Oral liquid preparation, adding 1% honey and other auxiliary materials to the supernatant liquid, and preparing the oral liquid after sterilization.

Embodiment 2

[0029] (1) Medicinal-based fermentation: add 15% apricot leaf ginseng extract to the above-mentioned basic medium, insert the Cordyceps taishan strain into the fermenter, shake and ferment at 140r / min, room temperature 20°C for 120h;

[0030] (2) Separation and extraction: Heat the above-mentioned drug-based fermentation product in a water bath at 100°C for 120 minutes, break the wall, take the supernatant, and concentrate it to 1 / 4 of the original volume;

[0031] (3) Oral liquid preparation, the supernatant liquid is added with auxiliary materials such as 10% honey, and the oral liquid is obtained after sterilization.

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Abstract

The invention discloses a preparation method of a Mount Taishan cordycep medical base fermented antitussive agent. According to the invention, Mount Taishan cordyceps are adopted as fermentation strains, and adenophora axilliflora is adopted as a constituent of a medical base medium. A liquid state fermentation method is adopted. A fermentation product is then processed, and an antitussive oral liquid is prepared. The antitussive agent brings substantial cough relieving, lung-heat clearing, and phlegm dissipating effects. As a result of experiments, a total effective rate of the antitussive agent reaches above 90%. Therefore, the antitussive agent has a high application value.

Description

1. Technical field [0001] The invention relates to the fields of traditional Chinese medicine and biotechnology-a preparation method of antitussive oral liquid. 2. Background technology [0002] Coughing is an important protective reflex of the human body, which can help clear respiratory secretions or foreign objects. On the other hand, if you suffer from a cold, bronchitis or other respiratory diseases, coughing will cause a series of harm to the human body. And it has the characteristics of long cycle, difficult to cure, and easy to cause various complications, such as exhaustion, hoarseness, urinary incontinence, etc., which seriously affects the patient's rest, work and study. In severe cases, the lungs may be ruptured, resulting in pneumothorax, with disastrous consequences. Cough makes people miserable and brings a lot of inconvenience to people's life, so antitussive medicine has become a must for families. [0003] There are many types of antitussive drugs on the...

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Application Information

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IPC IPC(8): A61K36/25A61K36/068C12N1/14A61P11/14
Inventor 聂心语蒋嘉琪苏延友
Owner 聂心语
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