Medicinal solution for prevention and treatment of chemotherapeutic phlebitis
A technique for chemotherapy phlebitis and medicinal liquid, which is applied in the directions of drug delivery, liquid delivery, and drug combination, can solve the problems of unsatisfactory treatment effect of chemotherapy phlebitis, high drug price, etc., and achieves low cost, wide drug source, good effect
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[0049] 1. Materials
[0050] (1) Experimental animals: 18 clean-grade Kunming mice, male and female, 5 weeks old, weighing 20.0±0.5g, Shanxi Cancer Institute (production license number: SCXX Jin 2007-0001).
[0051] (2) Drugs: fluorouracil (0.25g / 10ml, batch number: 090713 Shanghai Xudong Haipu Pharmaceutical Co., Ltd.); normal saline (0.9% sodium chloride injection, batch number R100511, Sichuan Kelun Pharmaceutical Co., Ltd.); liquid medicine of the present invention (Provided by Shanxi Cancer Hospital, batch number: 100719).
[0052] 2. Method
[0053] (1) Animal grouping: The animals were randomly divided into 3 groups, 6 in each group, half male and half male. Respectively positive control group, negative control group, liquid medicine group of the present invention.
[0054] (2) Membrane-making method: the positive control group and the liquid medicine group of the present invention injected 2.5mg / ml fluorouracil into the tail vein, 0.14ml / 10g body weight, that is, 35...
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