Medicinal solution for prevention and treatment of chemotherapeutic phlebitis

A technique for chemotherapy phlebitis and medicinal liquid, which is applied in the directions of drug delivery, liquid delivery, and drug combination, can solve the problems of unsatisfactory treatment effect of chemotherapy phlebitis, high drug price, etc., and achieves low cost, wide drug source, good effect

Inactive Publication Date: 2011-12-14
山西华尚汇商贸有限公司
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Problems solved by technology

[0009] The object of the present invention is to provide a kind of medicinal liquid for preventing and treating chemotherapeutic phlebitis in order to solve the problems such as the unsatisfactory therapeutic ef

Method used

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  • Medicinal solution for prevention and treatment of chemotherapeutic phlebitis
  • Medicinal solution for prevention and treatment of chemotherapeutic phlebitis
  • Medicinal solution for prevention and treatment of chemotherapeutic phlebitis

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[0049] 1. Materials

[0050] (1) Experimental animals: 18 clean-grade Kunming mice, male and female, 5 weeks old, weighing 20.0±0.5g, Shanxi Cancer Institute (production license number: SCXX Jin 2007-0001).

[0051] (2) Drugs: fluorouracil (0.25g / 10ml, batch number: 090713 Shanghai Xudong Haipu Pharmaceutical Co., Ltd.); normal saline (0.9% sodium chloride injection, batch number R100511, Sichuan Kelun Pharmaceutical Co., Ltd.); liquid medicine of the present invention (Provided by Shanxi Cancer Hospital, batch number: 100719).

[0052] 2. Method

[0053] (1) Animal grouping: The animals were randomly divided into 3 groups, 6 in each group, half male and half male. Respectively positive control group, negative control group, liquid medicine group of the present invention.

[0054] (2) Membrane-making method: the positive control group and the liquid medicine group of the present invention injected 2.5mg / ml fluorouracil into the tail vein, 0.14ml / 10g body weight, that is, 35...

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Abstract

The invention discloses a liquid medicament for preventing and treating chemotherapeutic phlebitis. The liquid medicament consists of the following bulk pharmaceuticals by weight: 50 grams of pseudo-ginseng root, 50 grams of rhubarb, 50 grams of rhizoma corydalis and 100 grams of red-rooted salvia root. The liquid medicament is prepared by the following steps of: drying and smashing the bulk pharmaceuticals to obtain fragments of which the diameters are 1-2 millimeters and the lengths are 1-2 centimeters; preparing the bulk pharmaceuticals according to the parts by weight of each bulk pharmaceutical, adding 800 ml of 60 percent ethanol and mixing uniformly; soaking at room temperature for 10 days and pouring out supernatant; adding 800 ml of 60 percent ethanol and mixing uniformly; soaking at room temperature for 10 days and pouring out supernatant; combining the supernatant obtained in two times and filtering; adding 400 ml of glycerin into a filtrate and mixing uniformly; and bottling the obtained 2,000 ml of liquid medicament and sealing for later use. The liquid medicament has the advantages of easiness for preparation, low cost, wide medicinal herbs resource, convenience for using, no toxic or side effect, good prevention and treatment effects on chemotherapeutic phlebitis and total effective rate 96 percent during clinical application.

Description

technical field [0001] The invention relates to a medicine for preventing and treating phlebitis caused by chemotherapeutic drugs, in particular to a medicinal solution for preventing and treating chemotherapeutic phlebitis. Background technique [0002] Malignant tumors are one of the three major diseases that endanger human health. Chemotherapy is the most commonly used treatment for patients with advanced malignant tumors. Chemotherapy drugs often cause different degrees of superficial phlebitis, which not only brings pain to patients, but also causes Chemotherapy did not go well. Although the operation technique of chemotherapy drug infusion has been significantly improved, which has played a certain role in reducing or preventing the incidence of chemotherapy drug extravasation, but due to repeated intravenous administration, phlebitis caused by chemotherapy drugs is inevitable. According to reports, the incidence of extravasation of chemotherapy administered via perip...

Claims

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Application Information

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IPC IPC(8): A61K36/708A61K9/08A61K9/10A61P9/14
Inventor 任连生王国平王晋芬张蕻杨喜花
Owner 山西华尚汇商贸有限公司
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