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Sub-pixel segmentation coding microscopy imaging device

An imaging device and coding technology, used in measurement devices, scanning probe microscopy, instruments, etc., can solve the problem that the resolution of the microscope cannot continue to improve the resolution and field of view, the control is difficult, and the imaging speed of the near-field optical microscope is slow. And other issues

Inactive Publication Date: 2011-12-14
HUAZHONG UNIV OF SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] The present invention proposes two kinds of sub-pixel segmentation coding microscopic imaging devices, which solve the problems of slow imaging speed and difficult control of existing near-field optical microscopes; There are contradictions in the scope of the field

Method used

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  • Sub-pixel segmentation coding microscopy imaging device
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  • Sub-pixel segmentation coding microscopy imaging device

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0148] Embodiment 1, M=3, N=5, the sub-arrays constituting the sub-wavelength pinhole array are 3rd order, and the number of columns necessary for encoding is P=2;

[0149] Such as figure 2 As shown, the image obtained by the area array photodetector is composed of 3×5 pixels, and each pixel is represented by the letters A~O; the sub-wavelength pinhole array is composed of 3×5 sub-arrays and 2 columns of small holes necessary for coding. Each sub-array is composed of holes, and each sub-array is composed of any row of a 3-row and 3-column cyclic s matrix composed of 0 and 1; the first row is 101,

[0150] When forming a subwavelength pinhole array, it is an array of 3 rows and 17 columns:

[0151] 10110110110110110

[0152] 10110110110110110

[0153] 10110110110110110,

[0154] or:

[0155] 01101101101101101

[0156] 01101101101101101

[0157] 01101101101101101,

[0158] or:

[0159] 11011011011011011

[0160] 11011011011011011

[0161] 11011011011011011,

[0162]...

Embodiment 2

[0165] Embodiment 2, M=3, N=5, the sub-arrays that make up the sub-wavelength pinhole array are 15 orders, and the number of additional columns necessary for encoding is P-1=14; each sub-array is composed of the same, all are composed of 0 and 1 Any row of the formed 15-row and 15-column cyclic s-matrix, the first row is 000100110101111; to simplify the expression, the following character correspondences: Octal 0, 1, 2, 3, 4, 5, 6, 7 respectively represent binary 000, 001 , 010, 011, 100, 101, 110, 111, the first line is 04657;

[0166] The subwavelength pinhole array is composed of 3 rows and 89 columns:

[0167] 04657046570465704657046570465+11

[0168] 04657046570465704657046570465+11

[0169] 04657046570465704657046570465+11;

[0170] In the above array, the two rightmost columns are in binary representation, and the remaining columns are in octal representation.

Embodiment 3

[0171] Embodiment 3, M=3, N=5, the sub-arrays forming the sub-wavelength pinhole array are 15 orders, and the number of additional columns necessary for encoding is 14;

[0172] Each sub-array is a 5×3 array, and the first row 000100110101111 of the 15-row and 15-column circular s-matrix composed of 0 and 1 is formed by folding 5 rows, and the folding method of 5 rows and 3 columns is:

[0173] 000

[0174] 100

[0175] 110

[0176] 101

[0177] 111

[0178] The first 5 rows of the corresponding subwavelength pinhole array are made as follows:

[0179] 00010011010111100010011010111

[0180] 10011010111100010011010111100

[0181] 11010111100010011010111100010

[0182] 10111100010011010111100010011

[0183]11100010011010111100010011010

[0184] Among them, the first 5 rows of the subwavelength pinhole array are constructed in the following way, from left to right:

[0185] 1st subarray, 2nd subarray, ... 3rd subarray, 5×14 additional subarrays,

[0186] In the 2nd to ...

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Abstract

The invention discloses two sub-pixel division coding microscopic imaging devices, which belong to the optical wave band microscopic detection imaging device. The problem that the conventional near-field optical microscope is slow to image and difficult to control is solved; and the problems that resolution of the conventional microscope cannot be continuously improved under restriction of optical diffraction and the contradiction exists between the resolution and view field range are solved. The device comprises a viewing window, a coding plate, a microscope objective and a plane array photoelectric detector; the coding plate is a quartz glass plate coated with a metal film on the surface or self-supporting metal film; the coated metal film or the self-supporting metal film is fabricatedwith a sub-wave length hole array; the aperture of each hole is smaller than r valve in Rayleigh criterion. The sub-pixel division and coding is carried out on each pixel in imaging region of the microscope objective, and then the valve of each sub-pixel is decoded from an image obtained by the plane array photoelectric detector; the device has large vision field and high resolution; the inherentcontraction between imaging resolution and vision field of the conventional microscope objective is broken.

Description

technical field [0001] The invention belongs to an optical band microscopic detection and imaging device. Background technique [0002] The existing imaging device, the optical microscope, uses uncharged photons as the information carrier, which has little interference with cells, and is a basic tool for biological and medical research. Although other types of microscopes, such as electron microscopes and scanning tunneling microscopes, already have sub-nanometer resolution, because the characteristic energy of electromagnetic waves in the optical band is similar to the molecular motion energy of biological substances, certain forms of interaction are prone to occur , so that these substances can be further understood through this interaction without damaging the biological activity of these substances. Therefore, many advanced laboratories in the world have been working hard to explore the characteristics of optical near-field imaging in order to use these characteristics ...

Claims

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Application Information

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IPC IPC(8): G01Q60/18
Inventor 叶梅叶虎年
Owner HUAZHONG UNIV OF SCI & TECH
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