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Traditional Chinese medicine composition for treating spleen and kidney deficiency type diabetic nephropathy and its preparation method and application

A technology for diabetic nephropathy and deficiency of both spleen and kidney, which can be used in drug combinations, pharmaceutical formulations, urinary system diseases, etc.

Inactive Publication Date: 2011-12-28
天津市石天药业有限责任公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The existing Chinese patent medicines for the treatment of diabetic nephropathy, or invigorating the spleen and removing dampness, or invigorating the kidney and absorbing essence, etc., have different emphases in the treatment, but all of them are unsatisfactory

Method used

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  • Traditional Chinese medicine composition for treating spleen and kidney deficiency type diabetic nephropathy and its preparation method and application
  • Traditional Chinese medicine composition for treating spleen and kidney deficiency type diabetic nephropathy and its preparation method and application

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preparation example Construction

[0030] The dynamic circulation multifunctional extraction and concentration equipment adopted by the preparation method of the traditional Chinese medicine composition of the present invention has the following specific operation steps:

[0031] a) water extraction: place the above-mentioned traditional Chinese medicine composition in a water extraction tank, add 6-10 times the amount of water of the traditional Chinese medicine composition by weight, preferably 8 times the amount of water and decocted for 2 times, 1-4 hours each time, The best time is 2 hours. After boiling, the steam pressure is 0.03-0.04Mpa, and the decoction is combined and filtered;

[0032] b) Concentration: the water-extracted filtrate is placed in a concentration tank, concentrated to a clear paste with a relative density of 1.29-1.31, a temperature of 50°C, and a concentration temperature of 40-100°C;

[0033] c) Preparation of granules:

[0034] a') The water extract is laid flat in a vacuum drying ...

Embodiment 1

[0042] Dodder Seed 200, Wine Schisandra 100, Rehmannia glutinosa 100, Astragalus 100, Sunburn Epimedium 50, Shilianzi 100, Salvia 50, Salt Plantain 50. The granules are prepared from the above prescription ratios and according to the preparation method of the above-mentioned traditional Chinese medicine composition.

Embodiment 2

[0044] Dodder Seed 400, Wine Schisandra 300, Rehmannia glutinosa 300, Astragalus 300, Sunburn Epimedium 250, Shilianzi 300, Salvia 250, Salt Plantain 200. The granules are prepared from the above prescription ratios and according to the preparation method of the above-mentioned traditional Chinese medicine composition.

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Abstract

The invention provides a traditional Chinese medicine composition for treating diabetic nephropathy with spleen and kidney deficiency. 300. Sunburn Epimedium 50-250, Echeveria 100-300, Salvia miltiorrhiza 50-250, Salt Plantago 50-200, and medicinal excipients. At the same time, it provides a preparation method of a traditional Chinese medicine composition for treating diabetic nephropathy with spleen and kidney deficiency, which is used for treating diabetic nephropathy. The effect of the present invention is that the traditional Chinese medicine composition overcomes the disadvantages of traditional dosage forms such as decoction, adopts the method of water extraction, retains the active ingredients with clinical curative effect in the composition, and adopts high-efficiency dynamic circulation extraction equipment to extract the active ingredients to the greatest extent , to ensure its clinical efficacy. The preventive and therapeutic effects on diabetic nephropathy with both spleen and kidney deficiency are obviously better than similar drugs.

Description

technical field [0001] The invention belongs to traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for treating spleen and kidney deficiency type diabetic nephropathy and a preparation method and application thereof. Background technique [0002] Diabetic nephropathy (DN) is a common complication of diabetes and one of the manifestations of systemic microangiopathy in diabetes (DM). The clinical features are proteinuria, progressive renal impairment, hypertension, edema, and severe renal failure in late stage. One of the leading causes of death in people with diabetes. In recent years, with the prolongation of life expectancy of the population in our country and the changes in living and eating habits and structure, the prevalence of diabetes has shown a linear upward trend, and kidney and other complications have also increased sharply. According to the latest statistics, about 60 million people in my country are currentl...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K36/88A61P3/10A61P13/12A61K35/32
Inventor 吴深涛李进周静崔维利王斌李庆书
Owner 天津市石天药业有限责任公司
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