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5% glucose adult nutrient solution and preparation method thereof

A technology of glucose and nutrient solution, applied in the field of medical drugs, can solve the problem of large fluctuation of blood sugar in patients, and achieve the effects of small fluctuation of blood sugar, complete metabolism and high energy supply

Inactive Publication Date: 2012-01-18
SHANXI NUOCHENG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are some glucose injections on the market, but when used in combination with other drugs, there are deficiencies such as large fluctuations in blood sugar and other metabolic complications caused by a single monosaccharide energy supply.

Method used

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  • 5% glucose adult nutrient solution and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A formula of 5% glucose nutrient solution for adults is as follows: 5000 mg of glucose, 234 mg of sodium chloride, 128 mg of potassium acetate, 32.2 mg of magnesium acetate tetrahydrate and 30 mg of sodium metabisulfite are added to 100 mL of water for injection.

[0019] The specific preparation method of the present embodiment comprises the following steps:

[0020] 1) Concentrated formulation: Take water for injection with a volume equal to 30% of the total volume of the formulated water for injection and a temperature of 70°C in the concentrated formulation tank, add the formulated amount of glucose and sodium chloride, stir to dissolve completely, and then add the concentrated formulation tank of traditional Chinese medicine Activated carbon with a liquid weight of 0.1%, heat-preserved and adsorbed at 70°C for 13 minutes, decarbonized and filtered, and sent to the dilute tank;

[0021] 2) Dilute formulation: Add potassium acetate, magnesium acetate tetrahydrate, an...

Embodiment 2

[0024] A formula of 5% glucose nutrient solution for adults is as follows: 5000 mg of glucose, 234 mg of sodium chloride, 128 mg of potassium acetate, 32.2 mg of magnesium acetate tetrahydrate and 30 mg of sodium metabisulfite are added to 100 mL of water for injection.

[0025] The specific preparation method of the present embodiment comprises the following steps:

[0026] 1) Concentrated formulation: Take water for injection with a volume equal to 33% of the total volume of the formulated water for injection and a temperature of 72°C in the concentrated formulation tank, add the formulated amount of glucose and sodium chloride, stir to dissolve completely, and then add the concentrated formulation tank of traditional Chinese medicine Activated carbon with a liquid weight of 0.1%, heat-preserved and adsorbed at 72°C for 11 minutes, decarbonized and filtered, and sent to the dilute tank;

[0027] 2) Dilute formulation: add potassium acetate, magnesium acetate tetrahydrate and...

Embodiment 3

[0030] A formula of 5% glucose nutrient solution for adults is as follows: 5000 mg of glucose, 234 mg of sodium chloride, 128 mg of potassium acetate, 32.2 mg of magnesium acetate tetrahydrate and 30 mg of sodium metabisulfite are added to 100 mL of water for injection.

[0031] The specific preparation method of the present embodiment comprises the following steps:

[0032] 1) Concentrated formulation: Take water for injection with a volume equal to 35% of the total volume of the formulated water for injection and a temperature of 75°C in the concentrated formulation tank, add the formulated amount of glucose and sodium chloride, stir to dissolve completely, and then add the concentrated formulation tank of traditional Chinese medicine Activated carbon with a liquid weight of 0.1%, heat-preserved and adsorbed at 75°C for 10 minutes, decarbonized and filtered, and sent to the dilute tank;

[0033] 2) Dilute formulation: Add potassium acetate, magnesium acetate tetrahydrate, an...

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Abstract

The invention belongs to the technical field of medical drugs, and particularly relates to a 5% glucose adult nutrient solution and a preparation method thereof. The invention mainly solves the defects that some glucose injections cause great fluctuation of blood sugar and are easy to cause metabolic complications. The technical scheme of the invention is that the formula of the 5% glucose adult nutrient solution is that the following components are added into 100 mL of injection water: 5000 mg of glucose, 234 mg of sodium chloride, 128 mg of potassium acetate, 32.2 mg of magnesium acetate tetrahydrate, and 30 mg of sodium pyrosulfite; and the 5% glucose adult nutrient solution is prepared by concentrated preparation, diluted preparation, filling and sterilization. The 5% glucose adult nutrient solution of the invention has the advantages of complete metabolism, high energy supply, and less blood sugar fluctuation.

Description

technical field [0001] The invention belongs to the technical field of medical medicines, and in particular relates to a 5% glucose adult nutrient solution and a preparation method thereof. Background technique [0002] Glucose is one of the main sources of heat for the human body. Sodium ions and chloride ions are important electrolytes for the human body. They mainly exist in extracellular fluid and play a very important role in maintaining the normal volume and osmotic pressure of blood and extracellular fluid in the human body. Normal people can meet the body's demand balance for glucose and electrolytes through daily diet, but for patients with lesions, due to abnormal body functions, special nutrient solutions are needed to meet the body's needs, especially for dehydration For patients with insufficient supply and demand of body water and electrolytes caused by other causes, as well as patients before and after surgery, the supplementation of energy, water and electrol...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61K9/08A61P3/02A61P3/12A61K31/7004A61K31/19
Inventor 张润成
Owner SHANXI NUOCHENG PHARMA
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