Traditional Chinese medicine composition for treating functional dyspepsia
A dyspepsia and functional technology, applied in the field of medicine, can solve side effects and other problems, achieve the effects of small side effects, rapid onset of effect, and convenient use and portability
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preparation example Construction
[0032] The Chinese medicine composition for treating functional dyspepsia is made into granules, and the specific steps of its preparation method are as follows:
[0033] S100, preparation of medicinal material extract:
[0034] S101. Place the medicinal materials of the prescribed amount in the extraction tank, add 8 times the amount of normal water (w / v), heat and reflux for 3 hours, filter, collect the filtrate, keep the medicinal residues, and then add 6 times the amount of water to the extraction tank ( w / v), heating to reflux for 2h, filtering, collecting the filtrate, and combining two batches of filtrate.
[0035] S102. Put the filtrate into a concentration tank, keep the temperature at 70-80°C, and concentrate under reduced pressure (vacuum degree 0.096MPa) until the relative density reaches 1.03-1.05 (75°C).
[0036] S103. With stirring, add 95% ethanol to the concentrated medicinal solution until the ethanol content is 65%, put it into a cold storage, keep it at 4°...
Embodiment 1
[0048] The consumption of each taste medicine raw material is as follows:
[0049] Scutellaria baicalensis 17kg Coptidis 17kg Phellodendron 17kg
[0050] Gardenia 17kg Radix Paeoniae Rubra 17kg Angelica 5kg
[0051] Chuanxiong 5kg Rehmannia glutinosa 5kg
[0052] A. The preparation method of medicinal material extract is as follows:
[0053] A1. Place the medicinal materials of the prescribed amount in a 1000L extraction tank, add 8 times the amount of normal water (w / v) (800L), heat and reflux for 3h, filter, collect the filtrate, keep the medicinal residues, and then add 6 Double the amount of water (w / v) (600L), heat to reflux for 2h, filter, collect the filtrate, and combine the two batches of filtrate;
[0054] A2. Put the filtrate into a 2000L concentration tank, keep the temperature at 70-80°C, and concentrate under reduced pressure (vacuum degree 0.096MPa) until the relative density reaches 1.25 (75°C);
[0055]A3. Under stirring, add 95% ethanol to the concentrate...
Embodiment 2
[0074] Experiments on Promoting Gastric Motility
[0075] experimental animals
[0076] Male Wistar rats, weighing 200±10 g, were purchased from the Experimental Animal Center of Sun Yat-sen University School of Medicine. Animal room temperature: 24±2°C; humidity 60±5%, light time 12 hours, fasting without food and water for 12 hours before the experiment.
[0077] experimental drug
[0078] Test drug: the granules in Example 1 are dissolved with deionized water, filtered, and the filtrate is prepared with deionized water into a 20mg crude drug / ml solution of the test product, stored at 4°C for subsequent use;
[0079] Positive control drug: cisapride suspension (Xi’an Janssen Pharmaceutical Co., Ltd., batch number AC1012002), made into a 5 × 10-2mg / ml solution with deionized water, stored at 4°C for future use;
[0080] Blank control: deionized water
[0081] Gastrointestinal markers: Dextran Blue-2000 (produced by Pharmacia), made into a 2% solution with deionized water....
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