Myocardial small molecular compound for idiosyncratically promoting proliferation of myocardial cells and application thereof
A technology of small molecular compounds and cardiomyocytes, applied in the field of medicine, can solve the problems of limited use and limited capacity of multifunctional stem cells
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[0018] The present invention is described in further detail below.
[0019] 1. Large-scale screening of active small molecule compounds through the model organism zebrafish.
[0020] Zebrafish, as a model organism, plays a very important role in multiple steps in the drug discovery process. The zebrafish is rapidly gaining acceptance as a promising animal model in toxicology research, and the ability to efficiently assess the toxicity of large numbers of compounds could allow entire compound libraries to be pre-screened for potential toxicity in advance. With this approach, compounds with significant toxicity can be eliminated from the compound library prior to high-throughput screening. Therefore, the screening of small molecular compounds based on embryo research in the present invention is carried out in the model organism zebrafish, and the small molecular compounds that can regulate the development and differentiation of embryos and organs are screened from the small mol...
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