Method for extracting liquiritigenin from liquorice

Abstract

The invention discloses a method for extracting liquiritigenin from liquorice. The method comprises the following steps of: (1) crushing the liquorice, extracting the powder by using 1 mol / L hydrochloric acid solution, filtering, regulating the filtrate to be neutral by using a 1 mol / L sodium hydroxide solution, and obtaining a crude liquiritigenin extract; and (2) injecting the crude liquiritigenin extract into a mixed resin column, and performing elution, separation, purification and re-crystallization. The liquiritigenin extracted by the method is a natural extract, and is high in purity, low in cost, high in production efficiency and stable and controllable in quality.

Description

technical field

[0001] The invention belongs to a method for extracting and purifying liquiritigenin, in particular to a method for extracting liquiritigenin from licorice. Background technique

[0002] Licorice is the dried roots and rhizomes of Glycyrrhiza uralensis Fisch., G. inflata Bata1., and G. glabra L. of the leguminous plants Glycyrrhiza uralensis Fisch. Clearing heat and detoxifying, eliminating phlegm and relieving cough, relieving spasm and relieving pain, and harmonizing the effects of various medicines. The flavonoids in licorice have a variety of biological activities. In addition to anti-inflammatory, antibacterial, and anti-allergic effects, they also have obvious effects on anti-oxidation, anti-cancer, anti-cancer, and anti-tumor. Modern pharmacological studies have shown that liquiritin, isoliquiritin, liquiritigenin and isoliquiritigenin are the main active ingredients of licorice flavonoids.

[0003] Liquiritigenin is an isomer of isoliquiritigenin, w...