Multi-mode low-coherence scattering spectrometer

Abstract

The invention discloses a multi-mode low-coherence scattering spectrometer, which is characterized by being provided with a white light source, a collimating light path and a polarizer. White light emitted from the white light source irradiates on a reflector after being collimated and polarized, reflected light from the reflector irradiates into an observed sample after transmitting a spectroscope, scattered light of the observed sample is reflected to a polarization analyzer through the spectroscope, light ray permeating the polarization analyzer is absorbed by a duct scope, a spectrometer is mounted along the focal length of the duct scope, a first CCD (charge coupled device) camera is connected to the spectrometer, a movable reflector is arranged between the duct scope and the spectrometer and used for reflecting light ray projected from the duct scope into a second CCD camera. The multi-mode low-coherence scattering spectrometer has the advantages that tissues can be detected noninvasively, variation of cell features caused by dyeing is avoided, structural information of shallow tissue and deep tissue can be acquired simultaneously by the polarization gating technology, spectrum, scattering angle, azimuth angle and polarization character of the tissues can be acquired simultaneously by means of wideband incidence of white light, and structural composition of the tissues can be described quantitatively.

Description

technical field [0001] The invention relates to a spectrometer, in particular to a multi-mode low-coherence scattering spectrometer for tissue cell measurement, which belongs to the optical imaging technology. Background technique [0002] Because traditional histopathological detection often needs to fix the tissue, stain it, and then observe the morphology and structure of the tissue cells through a microscope. A series of treatments may cause changes in the structure or characteristics of the tissue, resulting in insufficient reliability of the test results. At the same time, there is also a lack of quantitative parameters in the prior art to describe changes in tissue microstructures. Therefore, it is of great significance to non-invasively obtain the subdiffuse-scale optical scattering and absorption properties of biological tissue depth tomography to study the structure and composition of tissues. Contents of the invention [0003] The purpose of the present invent...

AI Technical Summary

Problems solved by technology

After a series of treatments, the structure or characteristics of the tissue may change, resulting in insufficient reliability of the test results

At the same time, there is also a lack of quantitative parameters in the prior art to describe the changes in tissue microstructure

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