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Traditional Chinese medicine composition for treating allergic rhinitis and preparation method thereof

A technology for allergic rhinitis and a composition, applied in the field of traditional Chinese medicine, can solve problems such as liver toxicity and high blood pressure, and achieve a remarkable effect

Active Publication Date: 2012-07-04
蚌埠丰原涂山制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, although ephedra has similar antihistamine effect and can expel symptoms such as nasal itching and sneezing, it can also cause high blood pressure and have certain toxicity to the liver.
Therefore, this traditional Chinese medicine composition is not suitable for hypertensive patients with allergic rhinitis

Method used

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  • Traditional Chinese medicine composition for treating allergic rhinitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: the spray for the treatment of allergic rhinitis

[0035] 1. Composition of traditional Chinese medicine: 15 parts of ginseng, 15 parts of Atractylodes macrocephala, 15 parts of poria cocos, 10 parts of cocklebur, 10 parts of asarum, 10 parts of black plum, 8 parts of Nepeta, 8 parts of Fangfeng, 5 parts of aconite, and 5 parts of dried ginger.

[0036] 2. Preparation method:

[0037] 1) Weigh 50Kg of medicinal materials according to the proportion, wash and soak, add 250kg of water to decoct 3 times, each time for 1 hour, filter after decoction, and combine the filtrate;

[0038] 2) Concentrate in vacuo to a specific gravity of 1.22, add 3 times the amount of the concentrated solution to ethanol precipitation with 90% ethanol for 18 hours, take the supernatant, let it stand and volatilize until there is no alcohol smell, add excipients Tween-80500g, potassium sorbate 200g, Appropriate amount of glycerin, after stirring and filtering, add water for inject...

Embodiment 2

[0040] Embodiment 2: Chinese medicine oral liquid for the treatment of allergic rhinitis

[0041] 1. Composition of traditional Chinese medicine: 15 parts of ginseng, 15 parts of Atractylodes macrocephala, 15 parts of poria cocos, 10 parts of cocklebur, 10 parts of asarum, 10 parts of black plum, 8 parts of Nepeta, 8 parts of Fangfeng, 5 parts of aconite, and 5 parts of dried ginger.

[0042] 2. Preparation method:

[0043] 1) Weigh 50Kg of medicinal materials according to the proportion, wash and soak, add 150kg of water to decoct 3 times, each time for 1 hour, filter after decoction, and combine the filtrate;

[0044] 2) Concentrate in vacuo to a specific gravity of 1.21, add 5 times the amount of concentrated solution in 90% ethanol to ethanol for 18 hours, take the supernatant, let it stand and volatilize until there is no alcohol smell, add 1000g of sucrose, 200g of sodium benzoate, stir and filter, then add Add water for injection to 50000ml to obtain oral liquid prepar...

Embodiment 3

[0046] Embodiment 3: Granules for the treatment of allergic rhinitis

[0047] 1. Composition of traditional Chinese medicine: 15 parts of ginseng, 15 parts of Atractylodes macrocephala, 15 parts of poria cocos, 10 parts of cocklebur, 10 parts of asarum, 10 parts of black plum, 8 parts of Nepeta, 8 parts of Fangfeng, 5 parts of aconite, and 5 parts of dried ginger.

[0048] 2. Preparation method:

[0049] 1) Weigh 50Kg of medicinal materials according to the proportion, wash and soak, add 500kg of water to decoct 3 times, each time for 1 hour, filter after decoction, and combine the filtrate;

[0050] 2) Concentrate in a vacuum until the specific gravity is 1.25, add 6 times the amount of 80% ethanol to ethanol for 18 hours, take the supernatant, let it stand and volatilize until there is no alcohol smell, and then add an appropriate amount of auxiliary materials into the spray drying granulator Starch 50kg, carboxymethyl starch sodium 80kg, carry out wet granulation, sieve an...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating allergic rhinitis and a preparation method thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicines in parts by weight: 10-20 parts of ginseng, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of tuckahoe, 5-15 parts of cocklebur fruit, 5-15 parts of asarum herb, 5-15 parts of dark plum, 3-10 parts of herba schizonepetae, 3-10 parts of radix sileris, 1-8 parts of monkshood and 1-8 parts of dried ginger. The traditional Chinese medicine composition provided by the invention can be used for treating allergic rhinitis and has an obvious effect, and the total effective rate reaches more than 90% which is superior to that of the existing products.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating allergic rhinitis and a preparation method thereof. Background technique [0002] Allergic rhinitis is a common and frequently-occurring disease, which is clinically defined as a series of nasal symptoms such as runny nose, nasal congestion, nasal itching, and sneezing triggered by IgE-mediated inflammatory response after the nasal mucosa is exposed to allergens. Allergic rhinitis is not a serious disease, but it involves a wide range of areas and is closely related to common allergic diseases such as bronchial asthma, sinusitis, and conjunctivitis. % of patients will develop bronchial asthma, or even emphysema, affecting quality of life. [0003] Currently, allergic rhinitis is treated with chemical drugs and specific immunotherapy in addition to avoiding contact with allergens. Chemotherapy mostly uses H1 rec...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P11/02A61P37/08
Inventor 郑嫣然余宏燕
Owner 蚌埠丰原涂山制药有限公司
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