Process for preparing 3,4-dimethylpyrazole phosphate

Abstract

The invention provides a process for preparing 3,4-dimethylpyrazole phosphate, which includes the steps: (1) reacting metallic sodium with 2-butanone and ethyl formate to produce 2-methyl-3-oxobutanoic acid sodium salt; (2) reacting hydrazine hydrate with the 2-methyl-3-oxobutanoic acid sodium salt to produce 3,4-dimethyl pyrazole; and (3) reacting the 3,4-dimethyl pyrazole with phosphoric acid to produce the 3,4-dimethylpyrazole phosphate. The process for preparing the 3,4-dimethylpyrazole phosphate has the advantages that raw materials are easy to obtain, reaction conditions are mild, the reaction time is short and by-products are few.

Description

technical field [0001] The present invention relates to a preparation method of 3,4-dimethylpyrazole phosphate, in particular to a preparation method capable of efficiently synthesizing 3,4-dimethylpyrazole phosphate Background technique [0002] In various agricultural production activities, people use a large amount of chemical fertilizers unreasonably in pursuit of crop yields. According to surveys, the current average annual amount of pure nitrogen in my country is 200kg / ha. In economically developed areas such as the Taihu Lake Basin, the annual amount of pure nitrogen applied reaches more than 600kg / ha, and in many areas, the amount of pure nitrogen used is even as high as 500-1300kg / ha. Nitrogen fertilizers are easily lost after application. In addition, the scope of agricultural activities is huge, and the non-point source pollution produced is far away. Much larger impact than industrial point source pollution. According to a survey, the total nitrogen loss rate of...

AI Technical Summary

Problems solved by technology

Although the two-step reaction of this scheme is carried out at room temperature, the reaction conditions are relatively mild, but the reaction time is relatively long, requiring 16-24 hours, and there will be isomers in the process of strong base catalysis to generate intermediate products, and there will be by-products in the end 3-Ethylpyrazole formation

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