The invention relates to a 
skin external preparation, in particular to an external preparation capable of promoting the active circulation of cells. The external preparation comprises the following components in percentage by 
mass: 20 to 50 percent of 
glycosaminoglycan, 20 to 50 percent of 
amino acid, 10 to 30 percent of natural extract, 5 to 10 percent of diguanosine tetraphosphate (Gp4g) and 1 to 5 percent of inorganic salt; and micro elements are added in an amount which is 0.001 to 0.05 percent based on the total 
mass of the previous components are added. The external preparation is prepared by using 
distilled water. The external preparation capable of promoting the active circulation of cells, which is provided by the invention, can be externally sprayed or applied on 
skin to quicklysupply inorganic salt to 
skin, activate cells and accelerate the 
metabolism of skin cells; and the external preparation also can 
supply energy and required water to cells, improve the micro circulation of skin and effectively clean free radicals, activate the self-healing 
system of 
human body, quickly penetrate and freely enter and leave cells, repair cells safely, naturally and gently, accelerate 
cell division, increase metabolic capacity and 
delay aging.