Medicine for treating lumbar disc herniation and preparation method thereof

A technology for herniated lumbar intervertebral discs and drugs, which is applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of complex preparation methods and many raw materials, and achieve good therapeutic effects, low recurrence rate, and non-toxic side effects

Active Publication Date: 2012-07-18
桂林华润天和药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, the invention patent with the publication number CN102125672A discloses a traditional Chinese medicine for treating cervical and lumbar diseases. Shell, Achyranthes bidentata, Notopterygium, Duhuo, Gentiana chinensis, Salvia miltiorrhiza, Shenjin grass, Luhan grass, Haifeng rattan, Sichuan pepper, Sophora japonica branch, willow branch, two tips, honeysuckle, Phellodendron cypress, Polyporus licorice, Peach kernel, Motherwort, Chuanconitum, Strychnis, Aconitum, Ground Beetle, Frankincense, Myrrh, Rehmannia glutinosa, Aescin, White Mustard Seed, Cinnamon, Yuanhu, Black Snake, Ce

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] 1) Take 160g of Duhuo, 120g of Sangjisheng, 160g of Angelica dahurica, 100g of Chuanxiong, 120g of Notopterygium, 120g of Caulis Caulis, 30g of Daxueteng, 30g of Sangzhi, 30g of Clematis, 30g of Sanqi, 30g of Astragalus, 160g of Angelica, 160g of Paeoniae Alba , Caulis Spatholobus 20g, Salt Eucommia 20g, Chuan Achyranthes bidentata 20g, Dipsacus 120g, Rhizoma Drynaria 120g, Dog Ridge 120g, Epimedium 30g, Cortex Phellodendron 20g and Pueraria 20g, mix evenly, crush to 10 mesh and mix with frankincense 20g Mix well with myrrh 10g, heat and reflux extract with 70% (v / v) ethanol for 3 times (for the first time, add ethanol with 6 times the weight of the raw material for 2 h, for the second time add ethanol with 4 times the weight of the raw material for 2 h, and for the third time Add 2 times of raw material weight ethanol to extract 2h), filter, merge filtrate, filtrate reclaims ethanol and is concentrated into the thick paste that relative density is 1.35 under 60 ℃, then ...

Embodiment 2

[0036] 1) Take 30g of Duhuo, 30g of Sangjisheng, 20g of Angelica dahurica, 20g of Rhizoma Chuanxiong, 30g of Notopterygium, 30g of Caulis Caulis, 180g of Daxueteng, 160g of Sangzhi, 160g of Clematis, 100g of Panax notoginseng, 100g of Astragalus, 30g of Angelica, 30g of Paeoniae Alba , Caulis Spatholobus 160g, Salt Eucommia 160g, Chuan Achyranthes bidentata 160g, Dipsacus 30g, Drynaria drynaria 30g, Dogji 30g, Epimedium 120g, Cortex Phellodendron 160g and Pueraria 160g, mix evenly, crush to 50 mesh and mix with frankincense 100g Mix well with 10 g of myrrh, heat and reflux with 95% (v / v) ethanol to extract twice (for the first time, add ethanol with 5 times the weight of the raw material for extraction for 2 hours, and for the second time, add ethanol with 3 times the weight of the raw material for extraction for 1 h), filter , merge filtrate, and filtrate reclaims ethanol and is concentrated into the thick paste that relative density is 1.05 under 60 ℃, adds menthol 100g and b...

Embodiment 3

[0038]1) Take 60g of Duhuo, 100g of Sangjisheng, 50g of Angelica dahurica, 60g of Rhizoma Chuanxiong, 60g of Qianghuo, 60g of Caulis Caulis, 60g of Daxueteng, 100g of Sangzhi, 60g of Clematis, 50g of Sanqi, 60g of Astragalus, 60g of Angelica, 60g of Paeoniae Alba , Caulis Spatholobus 60g, Salt Eucommia 70g, Sichuan Achyranthes bidentata 60g, Dipsacus 60g, Rhizoma Drynaria 60g, Dog Ridge 60g, Epimedium 70g, Phellodendron 60g and Pueraria 60g, mix evenly, crush to 30 mesh and mix with frankincense 30g Mix well with 30 g of myrrh, heat and reflux extract with 90% (v / v) ethanol for 3 times (for the first time, add ethanol with 4 times the weight of the raw material to extract for 1.5 h, for the second time add ethanol with 3 times the weight of the raw material for 1.5 h, For the third time, add ethanol with 3 times the weight of the raw material to extract for 1 h), filter, combine the filtrate, recycle the ethanol from the filtrate and concentrate it into a thick paste with a rel...

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PUM

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Abstract

The invention discloses a medicine for treating lumbar disc herniation and a preparation method thereof. The medicine is prepared by radix angelicae pubescentis, loranthus parasiticus, radix angelicae, ligusticum wallichii, notopterygium roots, caulis piperis futokadsurae, sargentg loryvine, ramulus mori, radix clematidis, pseudo-ginseng, astragalus mongholicus, angelica sinensis, radix paeoniae alba, caulis spatholobi, aalty cortex eucommiae, medicinal cyathula roots, teasel roots, drynaria rhizome, rhizoma cibotii, herba epimedii, golden cypress and pachyrhizua angulatus which are evenly mixed. After being crushed, the mixture is evenly mixed with frankincense and myrrh with the formula amount, and 70%-95% (V/V) ethanol is utilized to perform heating, reflux and extraction for two to three times. Each extraction lasts for one to three hours, filtrate is filtered and merged, the ethanol is recovered, the filtrate is concentrated to thick paste with relative density ranging from 1.05 to 1.35 under 60 DEG C, menthol crystal and borneol are added into the thick paste, and the thick paste is evenly stirred and then prepared into various different preparations. The medicine for treating lumbar disc herniation adopts more than twenty raw material medicines for matching and jointly increasing effects of nourishing liver, tonifying kidneys, removing coldness and damp, promoting qi, activating blood circulation and clearing and activating channels and collaterals, has good curative effects on a lumbar disc herniation disease, and has no side effects. The recurrence rate is extremely low.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a medicine for treating lumbar intervertebral disc herniation and a preparation method thereof. Background technique [0002] Lumbar disc herniation (lumbar disc herniation, LDH) is a common and frequently-occurring disease in orthopedics, and is the most common cause of low back pain. Most scholars believe that its pathogenesis is mainly related to injury and degenerative changes. On the basis of degenerative changes in the lumbar intervertebral disc, under the action of external force, the annulus fibrosus of the intervertebral disc ruptures, and the nucleus pulposus protrudes from the rupture, stimulating or compressing nerve roots and blood vessels. Or spinal cord and other tissues, or low back pain, sciatic nerve radiation pain, swelling, numbness, weakness and other symptoms caused by inflammatory stimulation. Because of its rapid onset and protracted...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/70A61P19/08
Inventor 张延惠王增谊莫有双张莹韦艺曾森
Owner 桂林华润天和药业有限公司
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