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Application of lincomycin in medicine for treating meniscus injury

A technology of lincomycin and meniscus, applied in the direction of drug combination, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problem of no reliable treatment and repair methods for meniscus, and achieve the effect of functional recovery

Inactive Publication Date: 2012-08-15
龚磊 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] And the injury of meniscus does not have reliable treatment, repair means in the prior art

Method used

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  • Application of lincomycin in medicine for treating meniscus injury
  • Application of lincomycin in medicine for treating meniscus injury
  • Application of lincomycin in medicine for treating meniscus injury

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0064] Drugs used:

[0065] The third generation display 20ml×1 tube;

[0066] 2% lidocaine needle 5ml×1 stick;

[0067] Sodium hyaluronate 2ml×2 sticks, produced by Shanghai Qisheng Biological Preparations Co., Ltd.;

[0068] Lincomycin 0.3g×2 sticks;

[0069] Dexamethasone 5mg×2 sticks;

[0070] 0.9% normal saline 500ml×4 bottles;

[0071] Lincomycin is relatively common, and the quality of each manufacturer has little difference.

[0072] Puncture method and surgical steps:

[0073] Routine local skin disinfection with povidone iodine, and routine draping. The medial midpoint of the patella was selected as the puncture point, and local anesthesia was performed with 2% lidocaine. Make a skin incision about 5mm long at the puncture point, puncture into the suprapatellar bursa through the incision, and inject a small amount of diluted contrast medium to confirm that the puncture needle has entered the suprapatellar bursa. Adjust the direction of the puncture needle to ...

Embodiment 2

[0076] Drugs used:

[0077] The third generation display 20ml×1 tube;

[0078] 2% lidocaine needle 5ml×1 stick;

[0079] Sodium hyaluronate 2ml×2 sticks, produced by Shanghai Qisheng Biological Preparations Co., Ltd.;

[0080] Lincomycin 0.3g×3 sticks;

[0081] Dexamethasone 5mg×2 sticks;

[0082] 0.9% normal saline 500ml×4 bottles;

[0083] Lincomycin is relatively common, and the quality of each manufacturer has little difference.

[0084] Puncture method and surgical steps:

[0085] Disinfection, puncture and other processes are the same as in Example 1, and then the joint fluid is completely sucked out and sent for inspection. Then lincomycin and dexamethasone were injected sequentially and slowly through the catheter, and sodium hyaluronate was injected after an interval of 1 minute. Finally, 2% lidocaine was used to flush the residual sodium hyaluronate in the catheter into the joint cavity. Extubation after confirming that there is no residual sodium hyaluronate ...

Embodiment 3

[0088] Drugs used:

[0089] The third generation display 20ml×1 tube;

[0090] 2% lidocaine needle 5ml×1 stick;

[0091] Sodium hyaluronate 2ml×3 sticks, produced by Bausch & Lomb Freda Pharmaceutical Co., Ltd., trade name Speight;

[0092] Lincomycin 0.3g×3 sticks;

[0093] Dexamethasone 5mg×3 sticks;

[0094] 0.9% normal saline 500ml×4 bottles;

[0095] Lincomycin is relatively common, and the quality of each manufacturer has little difference.

[0096] Puncture method and surgical steps:

[0097] Disinfection, puncture and other processes are the same as in Example 1, and then the joint fluid is completely sucked out and sent for inspection. Then inject lincomycin sequentially and slowly through the catheter, inject dexamethasone at intervals of 3 minutes, and inject sodium hyaluronate at intervals of 3 minutes; finally use 2% lidocaine to flush the residual sodium hyaluronate in the catheter into the joint cavity . Extubation after confirming that there is no resid...

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Abstract

The invention relates to medicine for treating meniscus injury, and also relates to sodium hyaluronate and lincomycin as well as the application of the lincomycin in the medicine for treating meniscus injury. The medicine for treating meniscus injury is characterized by comprising the lincomycin, wherein the lincomycin is a common fungistat in the prior art and can perform the action on fighting bacterium and diminishing inflammation. The medicine for treating meniscus injury finds that the lincomycin has the action on repairing a meniscus cell, and therefore the medicine for treating meniscus injury can serve as the medicine for repairing the meniscus injury and has a good curative effct. The medicine for treating meniscus injury is combined with the sodium hyaluronate and hexadecadrol, and has a better curative effect. The sodium hyaluronate serves as a nutrient substance to simultaneously perform the action on providing articular cavity pressure, supporting joint movement and lubricating joints, and is also convenient for dispersing other medicines, such as lincomycin. The hexadecadrol has the action on enhancing the medicine effect of the lincomycin. Several medicines are cooperated to perform a better treating effect.

Description

technical field [0001] The invention relates to a medicine for treating meniscus injury, and also relates to sodium hyaluronate and lincomycin. Background technique [0002] The menisci are two crescent-shaped fibrocartilages that lie on the medial and lateral articular surfaces of the tibial plateau. The anterior and posterior ends of the meniscus are attached to the non-articular surface of the middle part of the tibial plateau, anterior and posterior to the intercondylar spine, respectively. This part can also be called the anterior and posterior horns of the menisci. Its cross-section is triangular, thick on the outside and thin on the inside, slightly concave on the top to match the femoral condyle, and flat on the bottom to meet the tibial plateau. Such a structure just makes the femoral condyle form a deep depression on the tibial plateau, thereby increasing the stability of the spherical femoral condyle and the tibial plateau. That is, the function of the meniscus...

Claims

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Application Information

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IPC IPC(8): A61K31/7056A61K31/573A61K31/728A61P19/08
Inventor 龚磊罗鹏飞袁明远
Owner 龚磊
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