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Liver-protecting drop pill containing sweet potato flavone and preparation method of drop pill

A technology of flavonoids and sweet potatoes, which is applied in the field of Baogan dripping pills containing sweet potato flavonoids and its preparation, can solve the problems of not being retrieved, and achieve the effect of good effect, low cost and smooth appearance

Inactive Publication Date: 2012-08-15
QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Sweet potato flavonoids play an important role in protecting liver damage, but there is no relevant information on making sweet potato flavonoids into dripping pills, and it is necessary to study the proportioning relationship between sweet potato flavonoids and excipients, etc. Pay creative work; especially study the ratio relationship between sweet potato flavonoids and auxiliary materials through experiments, and make drop pills with better effect

Method used

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  • Liver-protecting drop pill containing sweet potato flavone and preparation method of drop pill
  • Liver-protecting drop pill containing sweet potato flavone and preparation method of drop pill
  • Liver-protecting drop pill containing sweet potato flavone and preparation method of drop pill

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] In this embodiment, each component is prepared according to the following ratio (unit: g)

[0016] Sweet Potato Flavone 15, Macrogol-6000 70, Macrogol-1000 15.

[0017] The preparation method of this embodiment is as follows: heat and melt the polyethylene glycol-6000 and polyethylene glycol-1000 of the above ratio on a water bath at 80°C, and stir evenly; Add it into the mixture, stir it well to make it evenly mixed, put it into a drop bottle, and drip it at 85±2°C; drop it into a glass condensation column filled with simethicone oil at 4-6°C, Take it out after forming, and use absorbent paper to absorb the adhering methyl silicone oil, that is to say.

Embodiment 2

[0019] In this embodiment, each component is prepared according to the following ratio (unit: g)

[0020] Sweet Potato Flavonoids 25, Macrogol-6000 70, Macrogol-1000 5.

[0021] The preparation method of this embodiment is as follows: heat and melt the polyethylene glycol-6000 and polyethylene glycol-1000 of the above ratio on a water bath at 95°C, and stir evenly; Add it into the mixture, stir it well to make it evenly mixed, put it into a drop bottle, and drip it at 85±2°C; drop it into a glass condensation column filled with simethicone oil at 4-6°C, Take it out after forming, and use absorbent paper to absorb the adhering methyl silicone oil, that is to say.

Embodiment 3

[0023] In this embodiment, each component is formulated according to the proportioning ratio in Table 1 (unit: g)

[0024] Table 1

[0025]

[0026] The preparation method of this example is as follows: heat and melt the polyethylene glycol-10000, polyethylene glycol-6000, and polyethylene glycol-1000 of the above ratio on a water bath at 85°C, and stir evenly; Add the sweet potato flavonoids in the above ratio into the mixture, stir well to make it evenly mixed, put it into a drop bottle, and drip it under the condition of 85±2°C; drop it into a container containing 4-6°C dimethyl In the glass condensation column of silicone oil, take it out after molding, and absorb the adhering methyl silicone oil with absorbent paper.

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PUM

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Abstract

The invention discloses a liver-protecting drop pill containing sweet potato flavone and the preparation method of the drop pill, belonging to the technical field of medicine preparation. The method comprises the following steps: heating and fusing polyethylene glycol-6000 and polyethylene glycol-1000 in water bath and evenly stirring; adding sieved sweet potato flavone and evenly stirring; putting the mixture obtained in the former step in a dropping bottle for dropping at the temperature of 85+ / -2 DEG C; dripping the mixture into a glass condensation column filled with simethicone for molding and then taking out; absorbing adhered methyl silicone oil with water absorbent paper; and packaging the finished products. The drop pill has the advantages of simple and practicable process, low cost, good product quality and excellent application effects.

Description

Technical field: [0001] The invention belongs to the technical field of medicine preparation, and relates to a liver-protecting dropping pill and a preparation method thereof, in particular to a liver-protecting dropping pill containing sweet potato flavonoids and a preparation method thereof. Background technique: [0002] The liver is the center of the body's material metabolism. When the liver function is damaged, the material metabolism will be disordered and the poisons will accumulate, which will be life-threatening in severe cases. Hepatitis is a very harmful disease. Many hepatitis patients develop hepatitis because they do not pay attention to the treatment of hepatitis. Liver cirrhosis and even liver cancer are life-threatening; therefore, it is particularly important to develop effective drugs against liver diseases; currently commonly used clinical drugs include antiviral drugs such as interferon lamivudine and matrine, immune drugs such as thymosin, glycyrrhizic ...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61K47/34A61K9/20A61P1/16
Inventor 韩彦弢陈雪红战松梅朱莉王春波
Owner QINGDAO UNIV