Implant
A technology of implants and needles, applied in the field of implants, can solve the problems of not being uniformly decomposed, screws not having sufficient mechanical strength, separation of hydroxyapatite and artificial joints, etc., to improve the initial bonding force and interface force Effect
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preparation example
[0089] Components having the component ratios given in Table 1 below were charged into a crucible made of stainless steel (SUS 410) and having an inner diameter of 50 mm. Then, while argon gas flows around the crucible so that the iron, nickel, manganese, aluminum, magnesium charged in the crucible does not come into contact with the air, the crucible is heated to a temperature of 700°C-750°C using a resistance heating furnace to melt the iron , Nickel, Aluminum, Manganese, Magnesium. The molten iron, nickel, aluminum, manganese, and magnesium are stirred by shaking the crucible so that they are easily mixed with each other. The completely molten magnesium alloy is cooled to produce solid magnesium alloy. In this case, in order to improve the mechanical strength of the solid magnesium alloy, the molten magnesium alloy was rapidly cooled by immersing the crucible in water (20° C.).
[0090] [Table 1]
[0091]
example 1
[0093] The biodegradable magnesium alloy of Preparation Example 1 was ground to obtain a powder having an average particle diameter of 500 μmu (hereinafter referred to as "biodegradable magnesium alloy powder").
[0094] Biodegradable magnesium alloy powder was mixed with a biodegradable polymer (LPLG (poly(L-lactide-co-glycolide))) in a volume ratio of 85:15. Thereafter, the mixture was pressed at a temperature of 200° C. and a pressure of 5 atmospheres to produce screw-shaped implants.
[0095] figure 2 is a photograph of an artificial joint fitted with an implant manufactured in Example 1.
[0096] refer to figure 2 , which accurately depicts the implant (arrow) installed in an artificial joint (trade name: Optigen, manufactured by Yon & I Corporation).
preparation example 1
[0098] The biodegradable magnesium alloy of Preparation Example 1 was extruded at an extrusion temperature of 400° C., and the compression ratio (extrusion ratio) of the cross-sectional area of the biodegradable magnesium alloy before and after extrusion was fixed at 15:1. The extruded magnesium alloy was processed to the extent that it could be transplanted into mice to create the implants.
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