Traditional Chinese medicine mixture for treating pediatric membranous nephropathy

A technology for primary nephropathy and traditional Chinese medicine, applied in drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve problems such as large side effects, uncertain efficacy of hormones and immunosuppressants, etc.

Inactive Publication Date: 2012-08-22
刘金彦
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, the efficacy of hormones and immunosuppressants is uncertain, and the side...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Example 1: Weigh 11g of plantago seed, 13g of coix seed, 8g of bellflower, 10g of Eupatorium, 10g of Achyranthes bidentata, 9g of three-edged root, 14g of astragalus, 8g of cistanche, 9g of epiyanghuo, 10g of sealwort, and 8g of atractylodes . Take the above-mentioned traditional Chinese medicine, add 850g of water to soak for 1 hour, boil twice for 30 minutes, get the filtrate, bottle and sterilize for future use.

Embodiment 2

[0027] Example 2: Weigh 10g of Plantaginaceae, 12g of Coix Seed, 7g of Bellflower, 9g of Eupatorium, 9g of Achyranthes bidentata, 7g of Sanleng, 13g of Radix Astragali, 7g of Herba Cistanche, 8g of Epiyang Huoxue, 9g of Polygonatum, and 7g of Atractylodes . Take the above-mentioned traditional Chinese medicine, add 800g of water to soak for 1 hour, boil twice for 30 minutes, get the filtrate, bottle and sterilize for future use.

Embodiment 3

[0028] Example 3: Weigh 12g of Semen Plantaginis, 15g of Coix Seed, 9g of Bellflower, 11g of Eupatorium, 12g of Achyranthes bidentata, 10g of Sanleng, 15g of Radix Astragali, 9g of Herba Cistanche, 10g of Herba Epimedium, 11g of Polygonatum, and 10g of Atractylodes . Take the above-mentioned traditional Chinese medicine, add 900g of water to soak for 1 hour, boil twice for 30 minutes, get the filtrate, bottle and sterilize for future use.

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Abstract

The invention discloses a traditional Chinese medicine mixture for treating the pediatric membranous nephropathy. The traditional Chinese medicine holds that the pediatric membranous nephropathy belongs to the 'edema' range and relates to the lung, spleen and kidney three-viscera malfunction. Most of the pediatric membranous nephropathy is mainly characterized by insufficiency of both the spleen and the kidney, blood stasis obstructing the collaterals and internal stagnation of fluid-dampness. The operations of treating the root and strengthening the body resistance serve as the principal, and the operations of warming kidney and eliminating damp are assisted on the basis of invigorating spleen, supplementing qi and invigorating the circulation of blood. Therefore, the traditional Chinesemedicine mixture for treating the pediatric membranous nephropathy is prepared from the following traditional Chinese medicines of plantain seed, semen coicis, rust-coloured crotalaria herb with root, herba lycopi, the root of bidentate achyranthes, rhizoma sparganii, astragalus mongholicus, boschniakia rossica, herba epimedii, rhizoma polygonati and rhizoma atractylodis, wherein the traditional Chinese medicines have the efficacy on tonifying Qi, lifting yang, removing blood stasis, and inducing diuresis to alleviate edema. The obtained traditional Chinese medicine mixture is taken by patients. According to the clinical test of our hospital, the total effective rate of the traditional Chinese medicine mixture is 93.3%, and a treatment group is obviously superior to a control group on theaspects of lowering cholesterol (CHOL) and urine protein and improving albumin (ALB) and clinic efficiency.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine mixture for treating primary nephropathy in children. Background technique [0002] Pediatric primary nephrotic syndrome is a common pediatric kidney disease. It is a clinical syndrome in which the permeability of the glomerular basement membrane is increased due to various etiologies and a large amount of protein is lost in the urine. The main features are massive proteinuria, hypoalbuminemia, severe edema, and hypercholesterolemia. According to its clinical manifestations, it is divided into three types: simple nephropathy, nephritis nephropathy and congenital nephropathy. In children under 5 years old, the pathological type of nephrotic syndrome is mostly minimal change type, while the pathological type of older children is mostly non-minimal change type (including mesangial proliferative nephritis, focal segmental sclerosis, etc.). ...

Claims

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Application Information

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IPC IPC(8): A61K36/902A61P13/12
Inventor 刘金彦
Owner 刘金彦
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