3-(2-naphthyl) acrylamide derivatives as well as preparation method and application thereof
A technology of acrylamide and its derivatives, which is applied in the field of 3-(2-naphthyl)acrylamide derivatives and their preparation and application, and can solve the problems of preventing the growth of malignant tumors, etc.
Inactive Publication Date: 2012-08-22
NANJING AGRICULTURAL UNIVERSITY
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AI-Extracted Technical Summary
Problems solved by technology
The invention discloses 3-(2-naphthyl) acrylamide derivatives as well as a preparation method and application thereof. 3-(2-naphthyl) acrylamide-like compounds are characterized by having the following general formula: in the formula, R is an aromatic base, a heterocyclic radical and the like. The compounds as inhibitors of an epidermal growth factor receptor (EGFR) can be applied to targeted therapy of tumor cells. The invention discloses the preparation method of the 3-(2-naphthyl) acrylamide derivatives.
Organic compound preparationCarboxylic acid amides preparation +1
Targeted therapyGrowth factor receptor +5
- Experimental program(15)
Description & Claims & Application Information
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