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Medicine composition used for preventing or treating senile dementia

A composition and senile technology, applied in the directions of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of high purity requirements and complex components of Acanthopanax senticosus extracts, and achieve definite and obvious curative effect, simple production process, Effects with few side effects

Active Publication Date: 2012-11-14
SICHUAN JISHENGTANG PHARMLS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent CN1528387A discloses that Rhodiola rosea extract is used to treat senile dementia, but it has only studied the effect of Rhodiola rosea extract obtained by different extraction methods on treating senile dementia; CN101810656A discloses that specific stimulant The extract of Acanthopanax is used to prevent and treat Alzheimer's disease, but the purity of the extract of Acanthopanax is very high
At present, most of the traditional Chinese medicines used to treat senile dementia are large prescriptions with complex components such as CN101269174A, CN101229293A, CN1266707A, CN1181966A, CN1478498A, etc. Therefore, it is very important to find traditional Chinese medicine prescriptions with simple components and definite curative effects

Method used

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  • Medicine composition used for preventing or treating senile dementia
  • Medicine composition used for preventing or treating senile dementia
  • Medicine composition used for preventing or treating senile dementia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] The preparation of embodiment 1 pharmaceutical composition

[0017] 1. Preparation of Acanthopanax senticosus extract

[0018] Take Acanthopanax raw medicine powder, add water to decoct and extract 3 times, first add 8 times the volume of water to decoct for 2 hours and filter, add 8 times the volume of water to decoct for 2 hours for the second time to filter, add 8 times the volume of water for the third time Decoct for 2 hours and filter, combine the filtrates, concentrate under reduced pressure, and dry to obtain the extract of Acanthopanax senticosus.

[0019] 2. Preparation of Rhodiola rosea extract

[0020] Take the original Rhodiola rosea powder, add 70% (v / v) ethanol and extract under reflux for 3 times, add 8 times the amount of 70% ethanol for the first time, extract for 2 hours; add 6 times the amount of 70% ethanol for the second time, extract For 1 hour, add 4 times the amount of 70% ethanol for the third time, extract for 1 hour, combine the extracted m...

Embodiment 2

[0023] The preparation of embodiment 2 pharmaceutical compositions

[0024] 1. Preparation of Acanthopanax senticosus extract

[0025] Take Acanthopanax crude drug powder, add water to decoct to extract, add 6-10 times the volume of water to decoct for 1-3 hours and filter for the first time, add 6-10 times the volume of water to decoct for 1-3 hours for the second time to filter, and the third time Add 6-10 times the volume of water each time, decoct for 0-3 hours, filter, combine the filtrate, concentrate under reduced pressure, and dry to obtain the extract of Acanthopanax senticosus.

[0026] 2. Preparation of Rhodiola rosea extract

[0027] Take the original Rhodiola rosea powder, add 50-75% (v / v) ethanol to heat and reflux extraction, add 4-8 times the amount of 50-75% ethanol for the first time, extract for 1-3 hours; add 4-8 times for the second time Double the amount of 50-75% ethanol, extract for 1-2 hours, add 4-8 times the amount of 50-75% ethanol for the third t...

Embodiment 3

[0030] Example 3 Preparation of Acanthopanax Radix Extract and Rhodiola Rosea Extract Pharmaceutical Composition Capsules

[0031] Take 100g of the pharmaceutical composition, 50g of the starch, and 100g of beta-cyclodextrin, mix them evenly, granulate and sieve, pack into capsules after drying to prepare the capsule of the pharmaceutical composition.

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Abstract

The invention provides a medicine composition used for preventing or treating senile dementia. Specifically, the invention provides a medicine composition composed of a manyprinckle acanthopanax extract and a kirilow rhodiola root and rhizome extract. The medicine composition is used for preventing or treating senile dementia. The invention also provides a preparation method of the medicine composition. The production process is simple. The medicine composition provided by the invention is advantaged in low medication dosage, convenient application, and low side effect.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine pharmaceutical compositions, in particular to a pharmaceutical composition for preventing or treating senile dementia. Background technique [0002] Alzheimer's disease can be divided into Alzheimer's disease (AD) and vascular dementia as well as mixed dementia. Nervous dysfunction is clinically manifested as deteriorating cognition and memory function, progressive decline in daily life ability, and various neuropsychiatric symptoms and behavioral disorders. Alzheimer's disease is a disease with a relatively high incidence rate. According to the data of the World Health Organization, there are about 20 million elderly people suffering from Alzheimer's disease in the world. It can be seen that Alzheimer's disease has threatened the health of human beings in their later years and reduced the quality of life in their later years. Families have brought serious economic burdens and heavy me...

Claims

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Application Information

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IPC IPC(8): A61K36/41A61P25/28
Inventor 柯尊洪高小平吴建明
Owner SICHUAN JISHENGTANG PHARMLS
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