Microfluidic chip for detecting early leukemia

A microfluidic chip and early detection technology, applied to laboratory containers, fluorescence/phosphorescence, laboratory equipment, etc., can solve the problems of unfavorable detection, high cost, large amount of blood samples, etc., to improve detection accuracy and detection efficiency, and the effect of reducing detection cost
CN102879377AInactive Publication Date: 2013-01-16CHONGQING UNIVERSITY OF SCIENCE AND TECHNOLOGY
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Patent Information

Authority / Receiving Office
CN Β· China
Current Assignee / Owner
CHONGQING UNIVERSITY OF SCIENCE AND TECHNOLOGY
Publication Date
2013-01-16
Estimated Expiration
Not applicable Β· inactive patent

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Abstract

The invention provides a microfluidic chip for detecting early leukemia. The microfluidic chip consists of two parts, namely a basic chip and a microfluidic detector; and the microfluidic chip is characterized in that the microfluidic detector is attached to the basic chip; a cell sorting element is processed on the microfluidic detector; a detection unit is a detection channel which consists of an electric field sorting device, cell capturing elements which are communicated with one another, a plasmid transfection element and a liquid collection tank; and more than 18 detection channels can be formed in one chip. Because a plurality of detection channels are assembled on the same chip, during the detection, more than ten subtypes of common leukemia of a patient sample can be detected on the same chip, so that the detection cost is greatly lowered, and the detection accuracy and detection efficiency are increased.
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Description

technical field

[0001] The invention relates to a novel medical detection chip, in particular to a microfluidic chip for early detection of leukemia used for diagnosing leukemia. technical background

[0002] Leukemia, commonly known as blood cancer, is a group of common hematopoietic primary malignant blood diseases, manifested as a significant decrease in normal hematopoietic cells and malignant transformation, malignant leukemia cells proliferate indefinitely and infiltrate bone marrow and other tissues, eventually resulting in a significant reduction in normal hematopoietic cells, Death occurred due to uncontrollable bleeding and infection. Clinically common acute leukemia is divided into three categories: acute lymphoblastic leukemia (ALL), acute myelolymphoblastic leukemia (AML) and special types of acute leukemia, with a total of 18 subtypes. In the early stages of this type of malignant disease, changes in the number, shape, and activity of marker proteins of differ...

Claims

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