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Recombinant hirudin storage bottle with ball

A technology for recombining hirudin and liquid storage bottles, which is applied in the field of medical devices, can solve problems such as ineffectiveness and reduced efficacy, and achieve the effects of convenient use, lowering blood lipids, and lowering blood viscosity

Inactive Publication Date: 2013-01-23
TIANJIN BAILIKANGTAI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Once the activity of hirudin is reduced to less than 30% or completely inactivated, its efficacy will be correspondingly reduced or even ineffective

Method used

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  • Recombinant hirudin storage bottle with ball

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] figure 1 It is a structural schematic diagram of the recombinant hirudin liquid storage bottle with balls of the present invention. Such as figure 1 As shown, the recombinant hirudin liquid storage bottle with rolling ball of the present invention includes a bottle cap 1 and a liquid storage bottle body 8, the bottom of the bottle cap 1 is connected with a bottle cap extension 11, and the inner side of the bottle cap 1 is near the lower end A concave bottle cap lock 2 is formed at the center, and the bottle cap lock 2 is connected to the protrusion formed on the outside of the bottle cap extension; the bottle cap extension 11 and the liquid storage bottle body 8 pass through the liquid storage bottle mouth 7 The thread 6 connection. The liquid storage bottle body 8 is filled with recombinant hirudin; the bottle cap extension 11 is provided with a ball 4 and a ball support rod 5, the upper part of the ball 4 protrudes from the top of the bottle cap extension 11, and th...

Embodiment 2

[0035] The using method of band ball recombined hirudin liquid storage bottle of the present invention is as follows:

[0036] (1) When using the product of the present invention, pull off the bottle cap 1 to disengage the bottle cap lock 2 from the bottle cap extension 11 . It is not necessary to squeeze the ball to make the hirudin liquid flow out, but by turning the ball, the liquid can flow out with the rolling of the ball. The ball is supported by the ball support rod, and the liquid flows to the ball through the gap between the ball and the support rod, and is used by rolling the ball. This design sacrifices part of the airtightness to improve the convenience of use, the steps of use are simple, and it is more convenient for patients to use. It is worth noting that due to factors such as age, disease, and limb defects, the ordinary action of squeezing the ball is still difficult for some patients, so appropriate compromises have to be made.

[0037] (2) When the recomb...

Embodiment 3

[0041] The invention further discloses the application of the recombinant hirudin liquid storage bottle with balls as a medical device in preventing the precursor of cerebral infarction. Especially in the treatment of cerebral embolism, cerebral hemorrhage, and stroke. Adopt the product of the present invention to carry out the experiment to typical cerebral embolism patient: stick a small amount of nursing solution on the acupuncture point suggested by the doctor with a scraping board, massage gently for 5-10 minutes, and the sticking nursing solution is all absorbed. The first 30 days are key care, once in the morning and once in the evening, and the next 60 days are general care, which can be changed to once a day, and 90-120 days is a course of treatment.

[0042] Case 1:

[0043] The patient is 45 years old, male, with high work pressure and frequent entertainment. Diagnosed by the hospital with hypertension 100-180, hyperlipidemia (triglyceride 2.5mmol / L, total cholest...

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PUM

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Abstract

The invention discloses a recombinant hirudin storage bottle with a ball. The storage bottle comprises a bottle cover and a storage bottle body, wherein a bottle cover extension part is connected with the lower part of the bottle cover; a concave bottle cover latch is formed on the part, which is close to the lower end of the bottle cover, of inner side of the bottle cover; the bottle cover latch is connected to a protruding part outside the bottle cover extension part; the bottle cover extension part and the storage bottle body are connected by threads at a storage bottle opening; recombinant hirudin is stored in the storage bottle body; a ball and a ball supporting rod are arranged in the bottle cover extension part, a liquid outlet cavity with a certain clearance is formed between the ball and the ball supporting rod and the inner wall of the bottle cover extension part; and the lower end of the ball supporting rod is connected to the storage bottle opening, and the ball supporting rod is supported by peripheral wall of the storage bottle opening. By the recombinant hirudin storage bottle, percutaneous drug delivery is realized, so that side effects of a medicine on a human body can be maximally reduced, and the recombinant hirudin storage bottle is safe and reliable in use. Moreover, the recombinant hirudin storage bottle can be used in any places at any time, and is beneficial to patients, and extra support is not required.

Description

technical field [0001] The invention belongs to the technical field of medical devices, and relates to a kind of device which uses recombinant hirudin r-HRD as the function of transdermal absorption. More specifically, a recombinant hirudin reservoir bottle with a roll-on ball. Background technique [0002] With the improvement of people's living standards, the speed of life, the unreasonable diet structure and the impact of my country's gradual entry into an aging society, the number of people suffering from cerebral embolism, hyperlipidemia, cerebral hemorrhage and other diseases is getting older and more serious. Seriously, it is gradually developing in the direction of younger age and younger age. Atherosclerosis and its thromboembolic complications have become the main causes of death and disability in both my country and Western countries. ) According to the latest statistics in 2002, about 17 million people die from various cardiovascular and cerebrovascular diseases ...

Claims

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Application Information

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IPC IPC(8): A61J1/05A61J1/14A61M35/00A61M37/00B65D83/00
Inventor 朱文娟刘晨刘金雪
Owner TIANJIN BAILIKANGTAI BIOTECH