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Pharmaceutical composition for cleaning and removing acne and preparation method of pharmaceutical composition

A technology for clearing and eliminating acne and a composition is applied in the field of a medicinal composition capable of clearing and eliminating acne and the field of preparation thereof, which can solve the problems of epidermal hypertrophy, large side effects, irritating use and the like, and achieve the effect of obvious therapeutic effect.

Active Publication Date: 2013-02-20
广西梧州三鹤药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There are many medicines for treating acne on the market, but there are not many medicines that can effectively treat acne, and most of these medicines that can effectively treat acne are western medicines, which have large side effects. The blood vessels are rapidly dilated and erythema appears, the epidermis is hypertrophic, and the use is irritating, so it is not suitable for long-term use

Method used

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  • Pharmaceutical composition for cleaning and removing acne and preparation method of pharmaceutical composition
  • Pharmaceutical composition for cleaning and removing acne and preparation method of pharmaceutical composition
  • Pharmaceutical composition for cleaning and removing acne and preparation method of pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Example 1: Preparation of Qingxiao Acne Capsules

[0017] The preparation method steps are as follows:

[0018] A, rhubarb is selected and pulverized, and the pulverized coarse powder is sieved with an 80-mesh sieve;

[0019] B. Mix raw land, burnet, dandelion, hedyotis diffusa, trichosanthum pollen, forsythia, mulberry bark and licorice, add water and decoct, boil for 2 hours, and filtrate; continue to add water to decoct the mixture, boil for 2 hours, and filtrate The mixture is decocted with water for the third time, boiled for 2 hours, and the filtrate is combined with the three filtered liquids, settled to remove impurities, and the filtrate is concentrated to a relative density of 1.30 to 1.35 at a temperature of 50°C to 70°C, adding the above-mentioned sieve Rhubarb powder, stirred and mixed, dried, drying temperature ≤ 80 ℃, pulverized into fine powder; finally filled to obtain capsules.

Embodiment 2

[0020] Embodiment 2: the preparation of Qingxiao acne granules

[0021] The preparation method steps are as follows:

[0022] A, rhubarb is selected and pulverized, and the pulverized coarse powder is sieved with an 80-mesh sieve;

[0023] B. Mix raw land, burnet, dandelion, hedyotis diffusa, trichosanthum pollen, forsythia, mulberry bark and licorice, add water and decoct, boil for 2 hours, and filtrate; continue to add water to decoct the mixture, boil for 2 hours, and filtrate The mixture is decocted with water for the third time, boiled for 2 hours, and the filtrate is combined with the three filtered liquids, settled to remove impurities, and the filtrate is concentrated to a relative density of 1.30 to 1.35 at a temperature of 50°C to 70°C, adding the above-mentioned sieve The rhubarb powder and appropriate amount of dextrin are stirred and mixed to make granules and dried at a drying temperature of ≤80°C to obtain granules.

Embodiment 3

[0024] Embodiment 3: the preparation of Qingxiao acne tablet

[0025] The preparation method steps are as follows:

[0026] A, rhubarb is selected and pulverized, and the pulverized coarse powder is sieved with an 80-mesh sieve;

[0027] B. Mix raw land, burnet, dandelion, hedyotis diffusa, trichosanthum pollen, forsythia, mulberry bark and licorice, add water and decoct, boil for 2 hours, and filtrate; continue to add water to decoct the mixture, boil for 2 hours, and filtrate The mixture is decocted with water for the third time, boiled for 2 hours, and the filtrate is combined with the three filtered liquids, settled to remove impurities, and the filtrate is concentrated to a relative density of 1.30 to 1.35 at a temperature of 50°C to 70°C, adding the above-mentioned sieve Rhubarb powder and appropriate amount of excipients (pharmaceutically acceptable excipients), stirred and mixed, made into granules, dried at a drying temperature ≤ 80°C; finally pressed into tablets, c...

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Abstract

The invention discloses a pharmaceutical composition for composition for cleaning and removing acne and a preparation method of the pharmaceutical composition, and relates to a medicament for treating the acne. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 320-400 of root of rehmannia, 260-350 of garden burnet root, 260-350 of dandelion, 250-320 of agkistrodon vaginalis, 250-320 of radices trichosanthis, 150-260 of fructus forsythiae, 100-230 of white mulberry root bark, 280-520 of rheum officinate and 50-80 of liquorice. The preparation method comprises the following steps: finely selecting and crushing the rheum officinate, and screening crude powder with a 80-mesh sieve; mixing the rehmannia, the garden burnet root, the dandelion, the agkistrodon vaginalis, the radices trichosanth, the fructus forsythiae, the white mulberry root bark and the liquorice, decocting for three times by adding water, and filtering solution; precipitating and removing impurities, concentrating filtrate at the temperature of 50-70 DEG C until the relative density is 1.30-1.35, adding the screened rheum officinate powder, stirring and mixing to obtain a mixture. A functional test proves that the acne capsule has obvious effect on acne caused by high heat of long and stomach and has no any side effects, and simultaneously, the acne capsule has the obvious treatment effect on sore in mouth, swollen sore throat, hot eye constipation, short and yellow urine and the like.

Description

technical field [0001] The invention relates to a medicine for treating acne, in particular to a medicine composition capable of clearing acne and a preparation method thereof. Background technique [0002] Acne is an inflammatory disease of the skin that often occurs on the face, chest and back of young men and women. It is called "lung wind acne" in traditional Chinese medicine. According to the age and location of the disease, the disease is mostly caused by youthful vigor, stomach heat and dryness of the lungs. , caused by steaming the face due to stagnant blood heat; the skin and hair are dominated by the lungs, dryness of the lungs and blood heat can cause skin rashes, redness, swelling and pain; the cheeks, nose, forehead, etc. are the places where the Stomach Meridian of Foot Yangming runs , and the stomach is a viscera with a lot of qi and blood, the stomach meridian accumulates heat, and the qi and blood components are all hot, and it goes up along the meridian and...

Claims

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Application Information

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IPC IPC(8): A61K36/748A61P17/10
Inventor 陈敏斐
Owner 广西梧州三鹤药业股份有限公司
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