Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and preparation method of traditional Chinese medicine

A technology of cardiovascular and cerebrovascular diseases and traditional Chinese medicine, applied in the field of traditional Chinese medicine formula, can solve the problems of large and narrow spectrum of side effects, high price, and difficulty in popularization, and achieve the effects of simple compatibility and preparation process, no toxic side effects, and low cost

Inactive Publication Date: 2013-05-01
NORTHWEST A & F UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although western medicine therapy has good curative effect, its side effects are large and narrow-spectrum. Surgical therapy is easy to leave surgical sequelae for patients. Dietary therapy is slow to take effect. Although commercially available Chinese medicine preparations have good curative effect, most of them have too complicated formulas and cumbersome preparation processes. Or due to the high price, there are certain problems such as difficulties in popularization, etc.

Method used

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  • Traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and preparation method of traditional Chinese medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Example 1: Take 300 grams of Salvia miltiorrhiza, cut into slices, then take 300 grams of sliced ​​hawthorn and 150 grams of safflower, mix the three ingredients and decoct with 2000 grams of boiling water for 2 hours, filter and take The filtrate was obtained as Danshanhong water extract. The method of taking is: 3 times a day, 300 grams of water extract each time.

experiment example

[0022] Experimental example: Establish a rat model of myocardial infarction, that is, artificially ligate the left coronary artery of the rat to cause acute myocardial ischemia or infarction, and evaluate the effect of Danshanhong water extract on the model of myocardial infarction ischemia or infarction.

[0023] Model establishment method: adult healthy male Sprague-Dawley, weighing 199g-226g, was randomly divided into administration group, model group and sham operation group. The administration group was further divided into three doses: high, medium and low. 10~15 in each group. Rats were anesthetized by intraperitoneal injection of 1% pentobarbital sodium at 50 mg / kg after weighing. for giving

[0024] In the drug group and the model group, the animals were fixed on the mouse board in the supine position, and the skin was prepared in the left chest area, and the skin was prepared by complexing iodine disinfection

[0025] In the area, tracheal intubation was performed...

Embodiment 2

[0049] Example 2: Take 200 grams of Salvia miltiorrhiza, 200 grams of hawthorn, and 100 grams of safflower. Mix the three ingredients and use

[0050] Pulverize into powder, then decoct with 1500 grams of boiling water for half an hour, filter and get the filtrate after decocting to obtain Danshanhong water extract.

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Abstract

The invention discloses a traditional Chinese medicine for treating cardiovascular and cerebrovascular diseases and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine comprises three raw materials, namely salvia miltiorrhiza, hawthorn and carthamus tinctorius. The traditional Chinese medicine can effectively alleviate myocardium conditions, has significant treatment effects on the cardiovascular and cerebrovascular diseases, particularly on chronic heart diseases, and has the advantages of simple preparation technology, lower cost, pure traditional Chinese medicine preparation, no toxic or side effects, and the like.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine formulas, in particular to a new traditional Chinese medicine formula for treating cardiovascular and cerebrovascular diseases. Background technique [0002] Cardiovascular and cerebrovascular diseases are a series of diseases involving the circulatory system. The circulatory system refers to the organs and tissues that transport blood in the human body, mainly including the heart and blood vessels (arteries, veins, microvessels). Cardiovascular and cerebrovascular diseases can be subdivided into acute and chronic cardiovascular diseases. Cerebrovascular diseases are generally related to arteriosclerosis. Myocardial cell necrosis and scar formation after myocardial ischemia injury lead to ventricular remodeling, deteriorating cardiac function, and eventually heart failure and death. Ventricular remodeling is mainly judged based on cardiac ejection fraction (EF), fractional shortening (...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61P9/00
Inventor 王永华李鹏汪纪楠周伟
Owner NORTHWEST A & F UNIV
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