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Broad-spectrum anti-parasitic compound ivermectin tablet for pets

An ivermectin tablet and anti-parasitic technology, which is applied in the direction of drug combination, anti-infective drugs, pill delivery, etc., can solve the problems of increasing infection of zoonotic parasitic diseases, etc., and achieves convenient administration methods and simple processes , the effect of increasing palatability

Inactive Publication Date: 2013-05-08
QINGDAO VLAND BIOTECH INC
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  • Summary
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  • Description
  • Claims
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AI Technical Summary

Problems solved by technology

However, people increase the chance of contact with pets in the process of raising and playing with pets, and also increase the possibility of being infected with zoonotic parasitic diseases

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] A broad-spectrum anti-parasitic compound ivermectin tablet for pets, the components and their weight and mass fractions are respectively (proportioned per 100g of raw materials):

[0013] Ivermectin 1 g

[0014] Praziquantel 2 g

[0015] Mannitol 45 g

[0016] Calcium carbonate 10.5 g

[0017] Dextrin 35g

[0018] Microcrystalline Cellulose 9.5 g

[0019] Preparation method: Take the prescribed amount of ivermectin and praziquantel and mix them with mannose to make granules, add the prescribed amount of lactose, calcium carbonate, dextrin, and microcrystalline cellulose, stir evenly, and further make granules with uniform granules The granules are sieved, and the obtained granules are compressed into tablets to obtain compound ivermectin tablets.

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PUM

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Abstract

The invention relates to a broad-spectrum anti-parasitic compound ivermectin tablet for pets and its preparation method. The tablet is composed of the following components by mass: 0.5%-1% of ivermectin, 1%-3% of praziquantel, 40%-70% of lactose, 10%-20% of mannitol, 15%-30% of calcium carbonate, 10%-20% of dextrin 400, and 1%-5% of microcrystalline cellulose. The tablet is prepared by subjecting the main drugs to mixing, filtering and tabletting. Compared with traditional anti-parasitic drugs, the broad-spectrum and high efficiency anti-parasitic tablets provided in the invention can be absorbed quickly through oral administration, can mitigate the hepatic first-pass effect, and can rapidly reach a maximum plasma concentration, thus achieving better clinical effects.

Description

technical field [0001] The invention relates to a compound ivermectin tablet for broad-spectrum anti-parasitic diseases for pets. It belongs to the field of veterinary medicine. Background technique [0002] With the continuous improvement of people's living standards, pet fever appears in many cities. Although keeping pets can bring fun to ordinary life, it can also be used as a kind of emotional sustenance to relieve people's loneliness and psychological pressure. However, people increase the chance of contact with pets in the process of raising and playing with pets, and also increase the possibility of being infected with zoonotic parasitic diseases. Parasites can spread a variety of diseases, causing unhealthy pets and owners, and can cause pet death in severe cases, especially pets with low immunity. [0003] Ivermectin is a new type of broad-spectrum, high-efficiency, and low-toxic antiparasitic drug, which has a good killing effect on internal parasites, especiall...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7048A61K31/4985A61K47/38A61K47/02A61K9/20A61P33/00
Inventor 郝智慧张瑞丽赵永达
Owner QINGDAO VLAND BIOTECH INC
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