Microbial culture medium prepared by using TCM (traditional Chinese medicine) waste residues, as well as applications and preparation method thereof
A technology for microbial culture medium and traditional Chinese medicine waste residues, applied in biochemical equipment and methods, botanical equipment and methods, microorganisms, etc., can solve problems such as differences in processing technology, loss of nutrients, and retention, and reduce production costs. Pollution problem, the effect of full utilization
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Embodiment 1
[0041] Embodiment 1——determination of mycoplasma polysaccharide content
[0042] The culture medium obtained in comparative examples 1-9 is used to cultivate Cordyceps militaris and Cordyceps sinensis respectively, and the culture medium obtained in each comparative example sets five experiments of repeatedly cultivating Cordyceps militaris and Cordyceps sinensis, and the culture method is to adopt the Cordyceps militaris strain liquid and Cordyceps fungus seed liquid were spread on the surface of the culture medium obtained in Comparative Example 1-9 respectively, and the obtained culture was based on 25-27 ℃ constant temperature and dark culture for 10-15 days, and after sampling each culture medium from the fifth day The obtained sample was dried and the polysaccharide content of the medicinal fungus was determined. The experimental conditions were as follows: the concentrated sulfuric acid-phenol method was used to detect the polysaccharide content, and the standard curve w...
Embodiment 2
[0043] Embodiment 2——Determination of content of mycoplasma cordycepin
[0044] Comparative example 1-9 gained substratum is used for cultivating Cordyceps militaris respectively, and the experiment of five repeated cultivation Cordyceps militaris is arranged in each contrasting example gained substratum, and culture method is to adopt that Cordyceps militaris seed liquid is scattered in contrasting example respectively 1-9 The surface of the obtained medium, and the obtained culture is based on constant temperature and dark culture at 25-27°C for 10-15 days. From the fifth day, each medium is sampled, and the obtained samples are dried and treated with the medicinal fungus Cordyceps sinensis Cordycepin content determination experiment, the experimental conditions are as follows: use high performance liquid chromatography to detect the content of cordycepin, the chromatographic conditions are Diamonsil C18 column (4.6mm*150mm, 5μm), with phosphate buffer (pH6.5) (take 0.01mol / ...
Embodiment 3
[0045] Embodiment 3 - the cultivation degree of culture medium of the present invention to different fungi
[0046] Utilize the experimental condition of embodiment 1 and experimental method that control example 4-9 is respectively used to cultivate Cordyceps militaris, saccharomyces, Staphylococcus aureus and detects the 7th day, the 9th day and the 11th day of the microorganism of each culture. The polysaccharide content was calculated as the average value, and the obtained results are shown in Table 4.
[0047] All the strains used above can be purchased in the market, or obtained from China Microorganism Culture Collection Center.
[0048] Table I
[0049]
[0050] Table II
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[0052] Table three
[0053]
[0054] Table four
[0055]
[0056] As can be seen from the experimental data in Table 1 and Table 2, when the culture medium of the present invention is cultivating microorganisms, the polysaccharide content in the fungal substance first increase...
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