Process for treatment of beta-lactam ring antibiotic filter residue
A lactam ring and antibiotic technology is applied in the technical field of processing beta-lactam ring antibiotic filter residues, which can solve problems such as environmental pollution, achieve good ecology and economic benefits, solve serious environmental pollution problems, and realize waste recycling. Effect
Inactive Publication Date: 2013-08-07
宋生
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Problems solved by technology
Dioxin, organic waste gas and other harmful gases are also produced during the combustion process, polluting the environment
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Embodiment Construction
[0017] In order to better understand the technical solution of the present invention, the following describes the embodiments provided by the present invention in detail.
[0018] The embodiment of the present invention provides a process for treating filter residue of β-lactam cyclic antibiotics, comprising steps:
[0019] Step 1. Isolation and screening of strains: Isolation and screening of strains resistant to β-lactam ring antibiotics capable of producing β-lactamase, purified and preserved;
[0020] The second step, preparation of medium: add corn starch 1%, yeast extract + peptone + urea (proportioned according to the mass ratio 2:2:1) 1%, manganese sulfate 0.5%, β-lactam to the fermenter Cyclic antibiotic filter residue 4%, water 93.5%, initial pH value 7.5, sterilized at 115°C for 30 minutes, then lowered to room temperature as a medium for later use;
[0021] The third step, preparing the β-lactamase liquid: inoculating the culture medium of the second step into the...
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The invention provides a process for treatment of beta-lactam ring antibiotic filter residue. The process comprises the steps of: strain isolation and screening; medium preparation; preparation of a beta-lactamase liquid; enzymolysis of the beta-lactam ring in residual antibiotic molecules of the filter residue; and once more fermentation treatment on beneficial microorganisms, thereby completely degrading the antibiotic residue in the beta-lactam ring antibiotic residue. The process for treatment of the beta-lactam ring antibiotic filter residue provided in the invention firstly prepares beta-lactamase to conduct enzymolysis on residual antibiotics in the filter residue, then performs beneficial microorganism fermentation, i.e. twice degradation, so as to remove the antibiotic residue in the filter residue thoroughly, and simultaneously decomposes thallus protein partially into small peptides, amino acids and other nutrient substances for further processing. Thus, the serious environment pollution problem caused by the residual antibiotics in the beta-lactam ring antibiotic filter residue is solved, and reuse of wastes is realized at the same time. Also, good ecological and economic benefits can be achieved.
Description
technical field [0001] The invention relates to the technical field, in particular to a process for treating filter residues of β-lactam ring antibiotics. Background technique [0002] The fermentation industry of β-lactam ring antibiotics is the main body of antibiotic production. During the production process, not only the antibiotics we need are produced, but also a large amount of antibiotic filter residues are formed. Analysis shows that there are still about 1000-1800IU / g of antibiotic residues (also known as drug residues). Due to the existence of problems such as drug residues, no reasonable disposal method has been found for antibiotic filter residues, causing serious environmental pollution. In the prior art, the treatment methods for antibiotic filter residues mainly include: [0003] One is that it is illegally directly used as raw materials for production of feed and organic fertilizers, which endangers food and ecological safety. The state has clearly prohibit...
Claims
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IPC IPC(8): A62D3/02A62D101/26
Inventor 宋生
Owner 宋生