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Natural drug composite, and preparation method and purpose thereof

A technology of natural medicines and compositions, applied in drug combinations, pharmaceutical formulations, antitumor drugs, etc., can solve the problems of patients with dehydration, acid-base imbalance, malnutrition, etc., and achieve increased inhibitory effect, enhanced inhibitory effect, and synergistic effect. obvious effect

Inactive Publication Date: 2013-10-02
石强
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Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural drug composite, and preparation method and purpose thereof

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Embodiment approach

[0035] The first step: preparation of various extracts

[0036] (1) Preparation of the concentrated extract of Astragalus yam decoction

[0037] Take astragalus and yam according to the compatibility ratio of 1:1, soak in distilled water, heat and decoct, filter, add distilled water to the medicinal residue, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate, and filter with an ultrafiltration membrane. Drying under reduced pressure, that is.

[0038] (2) Preparation of astragalus polysaccharide

[0039] Astragalus is crushed, extracted saponin with 95% ethanol, dried, added distilled water, and saturated lime water drop by drop, adjusted the pH value, left to stand for 10 minutes to moisten the material, irradiated with microwave for 1 minute, irradiated for 1 minute after an interval of 1 minute, and filtered to obtain the extract , repeat the above operation 2-3 times, combine the extracts, concentrate, adjust the pH=7 with 10% hydrochlo...

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Abstract

The invention relates to a natural drug composite, and a preparation method and a purpose thereof. The natural drug composite comprises an astragalus membranaceus Chinese yam decocted concentration extractive, astragalus membranaceus polysaccharide, a Chinese yam alcohol extractive and Chinese yam polysaccharide at a ratio of (2-5):(5-7):(3-7):(2-6). The composite has an extremely good curative effect on cancer chemotherapy relativity diarrhea, and can exert a synergetic effect on cancer chemotherapy.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of astragalus yam decoction concentrated extract, astragalus polysaccharide, yam ethanol extract and yam polysaccharide, the preparation method of the natural medicine composition And the use of the natural medicine composition in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated diarrhea...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P1/12A61P35/00A61K36/481A61K31/715
Inventor 石强
Owner 石强