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Natural pharmaceutical composition, and preparation method and application thereof

A technology of natural medicine and composition, applied in the direction of drug combination, pharmaceutical formula, antineoplastic drugs, etc., can solve the problems of dehydration, acid-base balance imbalance, malnutrition and other problems of patients, achieve increased inhibition, enhanced inhibition, and good side effects Effect

Inactive Publication Date: 2013-10-09
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural pharmaceutical composition, and preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment approach

[0032] The first step: preparation of various extracts

[0033] (1) Preparation of concentrated extract of psyllium tangerine peel decoction

[0034] According to the compatibility ratio of 1:1, take plantain seed and tangerine peel, add 10 times the amount of distilled water, soak for 1 hour, heat and decoct on the electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, add 6 times the amount of distilled water to the dregs, Soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a yellow powder, which is decocted and concentrated extraction of psyllium tangerine peel thing.

[0035] (2) Preparation of psyllium polysaccharide

[0036] Take plantago seed, extract with NaOH solution with pH of 9, filter the extract, adjust the filtrate to neutral with dilute hydrochloric ...

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Abstract

The invention relates to a natural pharmaceutical composition, and a preparation method and application thereof. The natural pharmaceutical composition is composed of Plantain seed / dried orange peel water-decocted concentrated extract, Plantain seed polysaccharide and nobiletin in a ratio of (3-7):(1-5):(5-8). The composition has excellent curative effects on diarrhoea related to cancer chemotherapy, and meanwhile, has a synergistic action on cancer chemotherapy.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition which is composed of plantago tangerine peel decoction concentrated extract, plantago polysaccharide and nobiletin, the preparation method of this natural medicine composition And the use of the natural medicine composition in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs are cytotoxic anti-tumor drugs, whether they are used alone or in combination, they will cause toxic and side effects such as diarrhea in patients. Diarrhea after ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P35/00A61P1/12A61K31/715A61K31/352
Inventor 石强
Owner 石强
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