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Natural pharmaceutical composition

A technology of natural medicines and compositions, applied in drug combinations, antitumor drugs, pharmaceutical formulations, etc., can solve the problems of patients with dehydration, acid-base balance disorders, malnutrition, etc., to enhance inhibition, increase inhibition, and synergize obvious effect

Inactive Publication Date: 2013-10-23
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural pharmaceutical composition

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Effect test

Embodiment approach

[0032] The first step: preparation of various extracts

[0033] (1) Preparation of the concentrated extract of andrographis chebula decocted in water

[0034] According to the compatibility ratio of 1:1 or 1-4:1, take Andrographis paniculata and Myrobalan, soak in 10 times the amount of distilled water for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, and recycle the dregs. Add 6 times of distilled water, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry in a vacuum oven at 70°C for 36 hours to obtain a brownish yellow powder, which is Andrographis paniculata decoct the concentrated extract.

[0035] (2) Preparation of andrographolide

[0036] Weigh an appropriate amount of Andrographis paniculata powder, pre-treat with enzymatic hydrolysis, soak in ethanol, filter, and recover ethanol to obtain extrac...

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Abstract

The invention relates to a natural pharmaceutical composition. The natural pharmaceutical composition is composed of an concentrated extract decocted with water of common andrographis herb and fructus chebulae, andrographolide and an extract of fructus chebulae extracted with 70% ethanol, wherein the ratio of the concentrated extract decocted with water of common andrographis herb and fructus chebulae, andrographolide and an extract of fructus chebulae extracted with 70% ethanol is (6-9):(3-6):(4-5). The composition has great effect on treating diarrhea related to cancer chemotherapy and also has synergism on the cancer chemotherapy.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is made up of andrographis paniculata chebula water decoction concentrated extract, andrographolide and chebula 70% ethanol extract, the natural medicine composition The preparation method and the application of the natural medicine composition in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs are cytotoxic anti-tumor drugs, whether they are used alone or in combination, they will cause toxic and side effects such as di...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/19A61P35/00A61P1/12A61K31/365
Inventor 石强
Owner 石强