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Chitin gel band-aid and preparation method thereof

A chitin and band-aid technology, applied in medical science, absorbent pads, bandages, etc., can solve the problem that wound care products cannot meet the requirements of the market, and achieve the effect of accelerating wound healing and reducing patient pain.

Active Publication Date: 2013-10-23
上卫中亚卫生材料江苏有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] With the increasingly fierce competition in the wound dressing industry, the current traditional wound care products have gradually failed to meet the requirements of the market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0033] On the other hand, the preparation method of chitin gel band-aid of the present invention, it comprises the steps:

[0034] (1) Weigh chitin as needed and dissolve in glacial acetic acid solution and stir to dissolve to obtain 1 # Intermediate;

[0035] (2) Weigh the gelatin as needed, add purified water, heat to 55-65°C, make the gelatin swell until transparent and keep it warm to obtain 2 # Intermediate;

[0036] (3) Weigh aluminum glyoxate as required, add it to glycerin, stir and mix to obtain 3 # Intermediate;

[0037] (4) Weigh sodium polyacrylate, sodium carboxymethylcellulose and K-90 as needed, place in a stainless steel mixing bucket, add glycerin, stir and mix well;

[0038] (5) Add purified water, turn on the machine and stir for 10 minutes, stop and store for 30 minutes;

[0039] (6) join 1 # intermediate and 2 # Intermediate, vacuumize and start stirring continuously for 3 hours, add 3 # The intermediate was stirred for 15 minutes to obtain a paste...

Embodiment 1

[0044] The hydrogel hemostatic dressing comprises the following components in percentage by weight: 0.5% chitin, 1.5% sodium polyacrylate, 5% sodium carboxymethylcellulose, 0.5% povidone, 0.5% gelatin, 0.05% aluminum glyoxate, Glycerin 20%, purified water 71.9% and glacial acetic acid 0.05%.

[0045] Weigh 0.5% of chitin as required, dissolve in 0.05% of glacial acetic acid, 3% of purified water and stir to dissolve to obtain 1 # Intermediate;

[0046] Weigh 0.5% of gelatin as required, add 3% of purified water, heat to 55°C, make the gelatin swell until transparent and keep warm to obtain 2 # Intermediate;

[0047] Weigh 0.05% of aluminum glyoxate as needed, add in 5% glycerin, stir and mix to obtain 3 # Intermediate;

[0048] Weigh 1.5% sodium polyacrylate, 5% sodium carboxymethylcellulose and 0.5% povidone as required, place in a stainless steel mixing bucket, add 15% glycerin, stir and mix evenly, and the stirring time is 2 minutes;

[0049] Add 65.9% of purified wate...

Embodiment 2

[0053] The hydrogel hemostatic dressing comprises the following components in percentage by weight: 2.75% chitin, 3.25% sodium polyacrylate, 7.5% sodium carboxymethylcellulose, 0.75% povidone, 1.25% gelatin, 0.28% aluminum glyoxate, Glycerin 30%, purified water 53.94% and glacial acetic acid 0.28%.

[0054] Take by weighing chitin 2.75% and dissolve in glacial acetic acid 0.28%, purified water 3% solution and stir to dissolve and make 1 # Intermediate;

[0055] Weigh 1.25% of gelatin as required, add 3% of purified water, heat to 60°C, make the gelatin swell until transparent and keep warm to obtain 2 # Intermediate;

[0056] Weigh 0.28% of aluminum glyoxate as required, add in 5% glycerin, stir and mix to obtain 3 # Intermediate;

[0057] Weigh 3.25% sodium polyacrylate, 7.5% sodium carboxymethylcellulose and 0.75% povidone as required, place in a stainless steel mixing tank, add 25% glycerin, stir and mix evenly, and the stirring time is 2 minutes;

[0058] Add purified...

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Abstract

The invention aims at disclosing a chitin gel band-aid and a preparation method thereof. The band-aid comprises a carrier, wherein the carrier is provided with hydrogel hemostasis surgical dressing, the hydrogel hemostasis surgical dressing comprises the following components by weight percentage: 0.5-5% of chitin, 1.5-5% of sodium polyacrylate, 5-10% of sodium carboxymethylcellulose, 0.5-1% of povidone, 0.5-2% of gelatin, 0.05-0.5% of dihydroxyaluminium aminoacetate, 20-40% of glycerinum, 36-71.9% of purified water, and 0.05-0.5% of glacial acetic acid. Compared with the prior art, the chitin gel band-aid has anti-inflammatory and sterilizing functions due to the combination of the wet environment and the effect of the chitin added into the gel, so that the wound can be healed quickly, the pain of a patient is reduced, and the purpose of the chitin gel band-aid is reached.

Description

technical field [0001] The invention relates to a band-aid and a preparation method thereof, in particular to a chitin gel band-aid and a preparation method thereof. Background technique [0002] Chitosan (CTS) is a natural organic polymer polysaccharide derived from shrimp and crab shells. It has good biocompatibility and hemostatic effect, and can prevent the formation of fibrin, the proliferation of connective tissue cells and the The synthesis of collagen has biological properties such as anti-inflammation, antibacterial, promoting wound repair, reducing scar hyperplasia, etc., and can play a hemostatic effect through various ways. It can also protect wounds and absorb wound exudate for large-area burns and scalds. Anti-inflammatory, sterilizing, hemostasis, analgesia, promotion of wound healing and skin regeneration, the above characteristics endow it with good performance as a wound hemostatic material. Chitosan (CTS) has become a hot spot in the research of new hemost...

Claims

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Application Information

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IPC IPC(8): A61L15/32A61L15/28A61L15/24A61L15/20A61L15/42A61L15/44
Inventor 周君兰雷怡叶承范
Owner 上卫中亚卫生材料江苏有限公司
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