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Anti-inflammatory drug for postpartum sow and preparation method thereof

A technology for breeding sows and anti-inflammatory drugs, applied in the field of medicine, can solve the problems of wasting feed, failing to discharge postpartum anti-inflammatory lochia, easy to discharge pus, etc.

Active Publication Date: 2013-11-13
福建奥姆龙生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The drug has the functions of invigorating the kidney and strengthening yang, promoting blood circulation and removing blood stasis, aphrodisiac and promoting pregnancy, etc. It has a good auxiliary effect on the involution of the postpartum uterus of sows, but it does not achieve postpartum anti-inflammatory and promotion of lochia discharge, resulting in many sows prone to bleeding during estrus Pus wastes feed and increases farming costs

Method used

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  • Anti-inflammatory drug for postpartum sow and preparation method thereof
  • Anti-inflammatory drug for postpartum sow and preparation method thereof
  • Anti-inflammatory drug for postpartum sow and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] First 10% of Naproxen and 30% of Metronidazole are pulverized and sieved to make it reach 100 mesh fineness, and then the above-mentioned pulverized 10% of Naproxen, 30% of Metronidazole and 2.0% of Gentamicin sulfate, 1.2% metoclopramide, 17.6% motherwort, 27.38% pottery clay, and 10% Daditian were poured into the wet granulator and rotated forward for 10 minutes, reversed for 10 minutes, and mixed evenly. Then add the prepared 1.82% starch, stir for 8 minutes, and finally put the stirred material into the swing granulator to granulate, and the granulated medicine is sent to the fluidized bed for drying through the negative pressure tube, and the drying temperature is 75 ℃, the drying time is 120 minutes, so that the water content of the granules is lower than 2%, and the dried medicine is sorted through a 18-60 mesh sieve, and packed.

[0024] The starch 1.82% is formulated into 5% starch slurry, and the steps are as follows: first, stir the starch evenly with 20% col...

Embodiment 2

[0026] First 9% Naproxen and 28% Metronidazole are pulverized and sieved to make it reach 100 mesh fineness, then the above-mentioned pulverized 9% Naproxen, 28% Metronidazole and 1.8% Gentamicin sulfate, 1.4% metoclopramide, 17.8% motherwort, 27.40% pottery clay, and 11% Daditian were poured into the wet granulator and rotated forward for 10 minutes, reversed for 10 minutes, and mixed evenly. Then add the prepared 1.84% starch, stir for 8 minutes, and finally put the stirred material into the swing granulator to granulate, and the granulated medicine is sent to the fluidized bed for drying through the negative pressure tube, and the drying temperature is 75 ℃, the drying time is 120 minutes, so that the water content of the granules is lower than 2%, and the dried medicine is sorted through a 18-60 mesh sieve, and packed.

[0027] The starch 1.84% is formulated into 5% starch slurry, and the steps are as follows: first, stir the starch evenly with 20% cold water, then add the...

Embodiment 3

[0029] First 11% Naproxen and 32% Metronidazole are pulverized and sieved to make it reach 100 mesh fineness, then the above-mentioned pulverized 11% Naproxen, 32% Metronidazole and 2.2% Gentamicin sulfate, 1.0% metoclopramide, 17.4% motherwort, 27.36% pottery clay, and 9% Daditian were poured into the wet granulator and rotated forward for 10 minutes, reversed for 10 minutes, and mixed evenly. Then add the prepared 1.80% starch, stir for 8 minutes, and finally put the stirred material into the swing granulator to granulate, and the granulated medicine is sent to the fluidized bed for drying through the negative pressure tube, and the drying temperature is 80 ℃, the drying time is 120 minutes, so that the water content of the granules is lower than 2%, and the dried medicine is sorted through a 18-60 mesh sieve, and packed.

[0030] The starch 1.80% is formulated into 5% starch slurry, and the steps are as follows: first, stir the starch evenly with 20% cold water, then add th...

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Abstract

The invention discloses an anti-inflammatory drug for a postpartum sow and a preparation method thereof. The preparation method comprises the following steps of crushing 9-11% of naproxen and 28-32% of metronidazole, sieving the crushed naproxen and metronidazole to obtain naproxen and metronidazole of 100 meshes, pouring 9-11% of the crushed naproxen, 28-32% of the crushed metronidazole, 1.8-2.2% of gentamycin sulfate, 1.0-1.4% of metoclopramide, 17.4-17.8% of motherwort, 27.36-27.40% of pottery clay and 9-11% of Daditian into a wet granulation machine, carrying out uniform mixing, adding 1.80-1.84% of starch into the mixture, carrying out stirring for 8min, pouring the stirred mixture into an oscillating granulator, carrying out granulation, feeding the granules into a fluidized bed by a negative pressure pipe, carrying out drying, and carrying out sieving and packaging.

Description

technical field [0001] The invention relates to a medicine, in particular to an anti-inflammatory medicine for postpartum sows. The invention also relates to a preparation method of the postpartum anti-inflammatory drug for sows. Background technique [0002] At present, such a postpartum anti-inflammatory drug for sows is disclosed on the market, which is the drug Epimedium 400g, Motherwort 400g, and Safflower 200g, which are made from the following weight ratio raw materials. The drug has the functions of invigorating the kidney and strengthening yang, promoting blood circulation and removing blood stasis, aphrodisiac and promoting pregnancy, etc. It has a good auxiliary effect on the involution of the postpartum uterus of sows, but it does not achieve postpartum anti-inflammatory and promotion of lochia discharge, resulting in many sows prone to bleeding during estrus Pus wastes feed and increases farming costs. Contents of the invention [0003] The purpose of the pr...

Claims

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Application Information

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IPC IPC(8): A61K36/533A61P15/00A61P29/00A61K31/166A61K31/4164A61K31/7036A61K31/192
Inventor 林振雁
Owner 福建奥姆龙生物工程有限公司
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