Traditional Chinese medicinal compound preparation for treating type 2 diabetes, and preparation method thereof

A technology of type 2 diabetes and compound preparations, which is applied in the direction of medical formulas, medical preparations containing active ingredients, metabolic diseases, etc., which can solve the problems of cumbersome medicine, exacerbation of chronic complications, huge social burden and economic burden, etc., and achieve improvement Pancreatic β-cell function, safe and effective administration, good results evaluated by patients

Inactive Publication Date: 2013-12-18
SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Type 2 diabetes is closely related to major diseases such as coronary heart disease, cerebrovascular disease, and tumors. Moreover, with the prolongation of the disease course, its chronic complications are increasing day by day, causing huge social and economic burdens
For

Method used

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  • Traditional Chinese medicinal compound preparation for treating type 2 diabetes, and preparation method thereof
  • Traditional Chinese medicinal compound preparation for treating type 2 diabetes, and preparation method thereof
  • Traditional Chinese medicinal compound preparation for treating type 2 diabetes, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1 Granules

[0018] Weigh raw materials: Coptidis 6 grams, Scutellaria baicalensis 9 grams, Pueraria 18 grams.

[0019] Preparation steps: take half of the above raw material, add 3 times the amount of water, soak for half an hour, decoct for 45 minutes, add 3 times the amount of water, decoct for 30 minutes, filter, combine the decoction liquid, concentrate under reduced pressure, and dry under reduced pressure to obtain Dried extract, crushed into fine powder (over 80 mesh). The other half of the raw material is crushed to 80 meshes, sterilized with CO60 (irradiation dose 8k), mixed with extract powder, added with mannitol, lactose, sucrose powder, aspartame, menthol, mixed with 60% ethanol Made into granules as a binder. Granules are 5g / bag, orally 2 times a day, 1 bag each time.

Embodiment 2

[0020] Embodiment 2 Granules

[0021] Weigh raw materials: Coptidis 3 grams, Scutellaria baicalensis 9 grams, Pueraria 15 grams.

[0022] Preparation steps: take half of the above raw material, add 8 times the amount of water, soak for half an hour, decoct for 45 minutes, add 8 times the amount of water, decoct for 30 minutes, filter, combine the decoction liquid, concentrate under reduced pressure, and dry under reduced pressure to obtain Dried extract, crushed into fine powder (over 80 mesh). The other half of the raw material is crushed to 80 meshes, sterilized with CO60 (irradiation dose 8k), mixed with extract powder, added with mannitol, lactose, sucrose powder, aspartame, menthol, mixed with 70% ethanol Made into granules as a binder. Granules are 5g / bag, orally 2 times a day, 1 bag each time.

Embodiment 3

[0023] Embodiment 3 granules

[0024] Weigh raw materials: Coptidis 6 grams, Scutellaria baicalensis 12 grams, Radix Puerariae 21 grams.

[0025] Preparation steps: take half of the above-mentioned crude drug, add 5 times the amount of water, soak for half an hour, decoct for 45 minutes, add 5 times the amount of water, decoct for 30 minutes, filter, combine the decoction liquid, concentrate under reduced pressure, and dry under reduced pressure to obtain Dried extract, crushed into fine powder (over 80 mesh). The other half of the raw material is crushed to 80 meshes, sterilized with CO60 (irradiation dose 8k), mixed with extract powder, added with mannitol, lactose, sucrose powder, aspartame, menthol, mixed with 65% ethanol Made into granules as a binder. Granules are 5g / bag, orally 2 times a day, 1 bag each time.

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Abstract

The invention belongs to the traditional Chinese medicine field, and concretely discloses a traditional Chinese medicinal compound preparation for treating the type 2 diabetes. The traditional Chinese medicinal compound preparation for treating the type 2 diabetes is prepared through adopting Radix Scutellariae, Rhizoma Coptidis and Radix Puerariae as primary medicines and mixing with auxiliary medicines. The invention also discloses a preparation method of the traditional Chinese medicinal compound preparation for treating the type 2 diabetes. Experiments show that the traditional Chinese medicinal preparation can adjust the glycometabolism of patients suffering from the type 2 diabetes, and can also improve the islet beta cell functions of the patients. The preparation can well treat the type 2 diabetes, and has the advantages of small dosage, appropriate price, safety and effectiveness after long-term taking, and good patient evaluation.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a compound traditional Chinese medicine preparation for treating type 2 diabetes and a preparation method thereof. Background technique [0002] Type 2 diabetes is a lifelong and slowly progressive disease. Its pathogenesis is: normal glucose tolerance→impaired glucose regulation→type 2 diabetes. The central link of the pathogenesis is insulin resistance and pancreatic β-cell dysfunction. Insulin resistance runs through the occurrence and development of type 2 diabetes, and β-cell dysfunction is a necessary condition for its pathogenesis. In fact, nearly 50% of the population is insulin resistant. But the incidence of diabetes is not parallel with insulin resistance, because β cells will compensatory secrete insulin to lower blood sugar. All patients with type 2 diabetes have impaired beta-cell function. The results of the Pima Indian study showed that ...

Claims

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Application Information

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IPC IPC(8): A61K36/718A61K31/7048A61P3/10A61K31/4375A61K31/352
Inventor 陶枫陆灏朱蕴华姚政张振华金昕
Owner SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M
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