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Medicine for treating cutaneous squamous cell carcinoma and preparation method of medicine for treating cutaneous squamous cell carcinoma

A squamous cell carcinoma, drug technology, applied in the direction of drug combination, pharmaceutical formula, medical preparation containing active ingredients, etc., can solve the problems of damage, formation of ulcers, high cost and so on

Active Publication Date: 2013-12-25
遵义医药高等专科学校
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the course of radiation therapy is long, and there is a potential risk of temporary skin redness, pain, and even ulceration; it can also lead to pigmentation, damage to surrounding tissues such as sweat glands, alopecia areata, and scar deterioration.
3 Drug treatment: Currently, there are imiquimod ointment, 5-fluorouracil ointment, injection of interferon, Bec-5 ointment, Pingyangmycin, cisplatin and other drugs for chemotherapy, but common skin redness, pain, desquamation, hardening Scab and other side effects
Laser treatment can be used alone or in combination with surgery, which is less time-consuming, but it needs to be done by a specialist, so it is expensive

Method used

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  • Medicine for treating cutaneous squamous cell carcinoma and preparation method of medicine for treating cutaneous squamous cell carcinoma
  • Medicine for treating cutaneous squamous cell carcinoma and preparation method of medicine for treating cutaneous squamous cell carcinoma

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A preparation method for a medicine for treating squamous cell carcinoma of the skin, comprising the steps of:

[0023] (1) 5 parts of pulsatilla, 3 parts of curcuma, and 2 parts of ginger, add 12 times the weight of medicinal materials and 70% ethanol to extract three times, each time for 2 hours;

[0024] (2) Combine the filtrates, concentrate them into a 1:1.3 liquid extract, dry them in a 65-75°C incubator until they become hard and brittle, and store them in low-temperature drying.

[0025]

Embodiment 2

[0027] A preparation method for a medicine for treating squamous cell carcinoma of the skin, comprising the steps of:

[0028] (1) 4 parts of pulsatilla, 4 parts of curcuma, and 1 part of ginger, add 12 times the weight of medicinal materials and 70% ethanol to extract three times, each time for 2 hours;

[0029] (2) Combine the filtrates, concentrate them into a 1:1.3 liquid extract, dry them in a 65-75°C incubator until they become hard and brittle, and store them in low-temperature drying.

[0030]

Embodiment 3

[0032] A preparation method for a medicine for treating squamous cell carcinoma of the skin, comprising the steps of:

[0033] (1) 6 parts of Pulsatilla chinensis, 2 parts of curcuma, and 2 parts of ginger, add 12 times the weight of medicinal materials and 70% ethanol to extract three times, each time for 2 hours;

[0034] (2) Combine the filtrates, concentrate them into a 1:1.3 liquid extract, dry them in a 65-75°C incubator until they become hard and brittle, and store them in low-temperature drying.

[0035]

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Abstract

The invention discloses a medicine for treating cutaneous squamous cell carcinoma and a preparation method of the medicine. The medicine comprises the following materials in parts by weight: 4-6 parts of roots of Chinese pulsatilla, 2-4 parts of curcuma zedoary and 1-3 parts of ginger. The preparation method of the medicine comprises the following steps: adding 70% ethanol into medicinal materials for extracting for three times, wherein the addition amount of ethanol is 12 times that of the medicinal materials and the extraction is carried out for 2 hours each time, combining filter liquor and concentrating to be fluid extract with the ratio of 1:1.3, placing into a thermotank with the temperature of 65-75 DEG C to dry into hard brittle pieces, and thus obtaining the medicine by storing at a low temperature and in a dry place. The medicine for treating cutaneous squamous cell carcinoma can obviously inhibit the proliferation of cutaneous squamous cell carcinoma A431 cells, meanwhile has effects on inducing the apoptosis of A431 cells, and also can prevent the cells from staying at a G0 / G1 period so as to prevent the DNA synthesis of an S period and inhibit the proliferation of tumor cells.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating skin squamous cell carcinoma, and also relates to a preparation method of the medicine for treating skin squamous cell carcinoma. [0002] Background technique [0003] Skin squamous cell carcinoma (SCC) is a malignant tumor originating from epidermal or adnexal keratinocytes. Its incidence is second only to basal cell carcinoma in non-melanoma of the skin, accounting for about 20% of all non-melanoma. The incidence of squamous cell carcinoma of the skin has been increasing year by year in recent years. The disease develops rapidly and is destructive. Lymph node metastasis can occur, and visceral metastasis can occur in the late stage. Skin squamous cell carcinoma has become the main skin tumor that threatens human life. [0004] The existing treatment methods for squamous cell carcinoma of the skin mainly include the following: 1. S...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61P35/00
Inventor 潘年松罗俊刘英波许俏
Owner 遵义医药高等专科学校
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