7 results about "Skin tumor" patented technology

The invention relates to the field of dermatology, and provides a rapid skin tumor resection tool aiming at the technical problem that an existing resection device is low in use efficiency, the rapid skin tumor resection tool comprises a shell with the inner area divided into a front end cavity, a middle end cavity and a rear end cavity, a front cover and a rear cover are rotationally connected to the positions, located outside the front end cavity and the rear end cavity, of the shell, the cutting device is arranged in the shell, and the cutting device comprises a high-pressure gas driving module which is arranged in the rear end cavity and extends to the middle end cavity; the homologous driving type displacement and rotary excision module is arranged in the front end cavity and is communicated with the high-pressure gas driving module; and the synchronous collection module is arranged in the front-end cavity. High-pressure gas is adopted as a power source of the excision device, generated chippings and blood can be blown away in time, the surgical field is kept in a clean state all the time, the tumor can be rapidly and accurately excided, and the use efficiency is high.

The invention discloses a skin tumor three-dimensional electrical impedance tomography method and device and a storage medium. The method comprises the following steps: acquiring a skin surface boundary voltage signal by using a planar electrode, and generating a space virtual electrode equivalent voltage through nonlinear mapping from a planar electrode domain to a space virtual electrode domain; mapping the voltage into a two-dimensional voltage feature map through bilinear interpolation, inputting the feature as prior information into a three-dimensional electrical impedance imaging reconstruction network, and performing depth matching inversion on the body area conductivity distribution based on a sliding window SwinUNet network to obtain a three-dimensional conductivity image; constructing a skin tissue finite element model, and generating a simulation data set; and training nonlinear mapping by adopting the simulation data set and verifying the depth matching inversion performance. The method can still keep stable reconstruction quality under uncertain conditions such as poor electrode contact, channel loss and skin structure change, has high robustness and adaptability, and has good clinical application value.

The application provides a kind of liposome nano-reactor loaded separation microneedle and its preparation method and application, belong to the field of biological medicine.The application uses phospholipid, cholesterol, tetramethoxysilane and 3-aminopropyl triethoxysilane as raw material, encapsulates cisplatin, 5-aminoacetylpropionic acid and catalase, and prepares liposome nano-reactor;With polyvinylpyrrolidone, citric acid, sodium bicarbonate and regenerated silk fibroin as raw material, the liposome nano-reactor is dispersed in microneedle body by pouring method, and a kind of microneedle that can be quickly separated is successfully prepared.The experimental research of the application proves that the separation microneedle has good biocompatibility and mechanical property, can effectively break through the stratum corneum, realize the efficient transdermal delivery of liposome nano-reactor.The liposome nano-reactor can be locally planted in deep tissue of tumor, continuously supply oxygen through enzymatic reaction, effectively improve the oxygen supply shortage of tumor photodynamic therapy, and has obvious advantages and broad prospects in the application of skin tumor photodynamic therapy.

The utility model relates to the technical field of tumor radiation, and particularly discloses a head, neck and shoulder positioning auxiliary device which comprises a fixing base. The abutting seat is arranged at the top end of the fixed seat, a plurality of limiting insertion rods are arranged outside the abutting seat, a thermoplastic film is fixedly connected to the outside of the abutting seat, air holes are formed in the outside of the thermoplastic film, a plurality of irradiation holes are formed in the outside of the thermoplastic film, and a plurality of compensation films are buckled to the outside of the thermoplastic film; by means of the abutting seat, the limiting inserting rod, the thermoplastic film and the air holes, the air holes are formed outside the thermoplastic film, the mouth and nose of a patient can be exposed, the comfort degree of the patient after wearing is improved, the compensation film can be conveniently buckled outside the thermoplastic film, and the comfort degree of the patient is improved. And treatment operation can be performed on patients under different conditions, so that the comfort of the patients is ensured, and the skin tumor irradiation dose is also ensured.

This invention discloses the fabrication of a wearable microneedle sensor and its application in the early visual detection of in situ melanoma. The invention first prepares gold-etched cuprous oxide and silver-encapsulated nanoparticles, then loads them with the small molecule compound catechol, and finally combines this with microneedle technology to create a wearable microneedle sensor. This microneedle sensor integrates colorimetric visualization and surface-enhanced Raman scattering (SERS) dual-mode detection, enabling in-situ sampling of living organisms. It can reflect physiological states in real time and continuously, providing an effective approach for the early diagnosis of skin tumors such as melanoma.

The application relates to the technical field of data processing, and particularly discloses a heterogeneous data feature extraction method and system based on multi-modal information fusion, which comprises the following steps: S1, collecting multi-source pathological data, determining a skin tumor disease set and multiple disease pathological data, and acquiring historical patient data; S2, determining multiple historical staging data and disease development vectors of each skin tumor disease; S3, determining a disease course development vector of each patient of each disease staging label of each skin tumor disease; S4, calculating a label feature set of each disease staging label of each skin tumor disease and multiple staging-course feature sets; and S5, constructing a disease detection model and multiple disease course development prediction models of each skin tumor disease. The core features of diseases and stages can be accurately refined, full-chain information support from disease identification, stage judgment to progress prediction is provided for the clinic, and the accuracy and foresight of skin tumor diagnosis and treatment are improved.

The application provides a flexible irreversible electroporation electrode patch for skin tumor treatment, which comprises a flexible electrode body, an electrode fixing adhesive, a release film, a cable fixing adhesive, a cable and a terminal. The flexible electrode body is composed of a 10-30 mu m thick polyimide film (PI) insulating substrate and a cover film clamping etched copper foil conductive circuit, the two ends of the circuit are respectively connected with a flexible conductive contact and a cable, the electrode fixing adhesive (diameter 50 mm with 3 split grooves) and the cable fixing adhesive respectively fix the patch and the cable, and the terminal is connected with a treatment host. The working electrode (4 evenly distributed in a 14-20 mm distribution circle) can be combined and switched in multiple groups, and is suitable for different sizes of skin tumors. The flexible electrode patch has good flexibility and stable fixation, can accurately control the electric field and the ablation range, avoids current mis-conduction, ensures safe and efficient treatment, and provides a special electrode scheme with strong adaptability and remarkable curative effect for irreversible electroporation treatment of skin tumors.