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Balloon dilatation catheter

A technique for dilating catheters and balloons, which can be used in balloon catheters, dilators, and surgery. It can solve the problems of microneedles that cannot accurately control the injection depth, drug loss, and easy drug loss, so as to avoid the risk of falling off and achieve precise control. , the effect of good fixed effect

Active Publication Date: 2013-12-25
SHENZHEN SALUBRIS BIOMEDICAL ENG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008]In view of the fact that the drug-coated balloon catheter surface prepared by the prior art is easy to lose the drug, and the injection depth cannot be precisely controlled by microneedles with different curved arcs, the ordinary balloon is directly used Due to technical problems such as difficulty in completely retracting the microneedles after injection of the drug, the purpose of the present invention is to provide a balloon dilatation catheter containing multiple microneedles, so that the microneedle injection depth can be precisely controlled and uniform drug delivery can be achieved; It can make the drug delivered by it be delivered inside the catheter, avoid the loss of drug during device intervention, and enable the microneedle to be fully retracted

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Balloon dilatation catheters are divided into proximal and distal ends, such as figure 1 and figure 2 As shown, there are two conduits, which are connected in a coaxial manner, such as image 3 shown. Wherein, the outer catheter 1 has a diameter of 2.5 mm, the inner catheter 2 has a diameter of 0.5 mm, and the distal end of the inner catheter is connected with an injection microneedle for drug delivery. The balloon-like actuator 3 is in the shape of a dumbbell, and the actuator is made of materials with different elastic moduli, among which the dumbbell-shaped depression 5 is made of PET with a first elastic modulus of 2500MPa, and the other parts are made of PEBAX with a second elastic modulus of 700MPa Made, wherein the first elastic modulus is greater than the second elastic modulus 1800MPa. The tube blanks of the two elastic materials are respectively placed in molds of corresponding size and shape, and the mold is placed in a heated heat-conducting medium, and...

Embodiment 2

[0054] Balloon dilatation catheters are divided into proximal and distal ends, such as figure 1 figure 2 As shown, there are two conduits, which are connected in a coaxial manner, such as image 3 shown. Wherein, the outer catheter 1 has a diameter of 0.75 mm, the inner catheter 2 has a diameter of 0.25 mm, and the distal end of the inner catheter is connected with an injection microneedle for drug delivery. The actuator 3 similar to the balloon structure is dumbbell-shaped, and the actuator is made of PEBAX, a material with the same elastic modulus. The dumbbell-shaped actuator is connected to the distal end of the outer catheter 1, and the microneedle 6 is first fixed on the On the sieve mechanism 7 made of nylon, such as Figure 8 and Figure 9 As shown, the sieve-like mechanism 7 is then fixed on the bottom 4 of the dumbbell-shaped depression by an adhesive cyanoacrylate.

[0055]

Embodiment 3

[0057] Balloon dilatation catheters are divided into proximal and distal ends, such as figure 1 and figure 2 As shown, there are two catheters, which are respectively connected in a coaxial manner, and two consecutive dumbbell balloons are shown as Figure 4 shown. Wherein, the outer catheter 1 has a diameter of 5 mm, the inner catheter 2 has a diameter of 1 mm, and the distal end of the inner catheter is connected with an injection microneedle for drug delivery. The actuator 3 similar to the balloon is two consecutive dumbbell shapes, and the actuators are made of materials with different elastic moduli. Among them, the dumbbell-shaped depression 5 is made of nylon with a first elastic modulus of 1000MPa, and the other parts are made of a second elastic modulus. Made of 800MPa PEBAX, where the first elastic modulus is greater than the second elastic modulus of 200MPa. The tube blanks of the two elastic materials are respectively placed in molds of corresponding size and ...

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Abstract

The invention relates to the field of medical instruments, and provides a preparation method of a balloon dilatation catheter which can be provided with a plurality of micro-needles. The balloon structure is in the shape of a dumbbell, a three-pointed star, a four-pointed star, a five-pointed star or a starfish or is in a deformed shape thereof; a first elastic modulus material is adopted at a sunken part of a multi-pointed star or a deformed shape thereof, and a second elastic modulus material is adopted on the other parts; the first elastic modulus is greater than the second elastic modulus; the micro-needles are arranged at the bottom of the sunken part of the multi-pointed star or the deformed shape. According to the balloon dilatation catheter with multiple micro-needles prepared by the method, each micro-needle can freely stretch out or fully retract, unnecessary damage caused to blood vessels by incomplete retraction of the micro-needles is fully avoided, the injection depth of the micro-needles can be accurately controlled, and the safety of angioplasty is improved.

Description

technical field [0001] The invention relates to a medical device, in particular to a balloon expansion catheter used for interventional treatment of vascular diseases. Background technique [0002] The emergence of vascular stents has ushered in a new era of vascular treatment for coronary heart disease. However, the clinical application of more and more stents has encountered a thorny problem: In Stent Restenosis (ISR). In the era of drug-eluting stents, ISR still occurs from time to time, and once it occurs, there is a lack of effective treatment methods. Overlaying another drugged stent within a restenotic drugged stent increases the rate of subsequent restenosis by as much as 43%. In recent years, new devices and treatment strategies have emerged to overcome this problem. Drug-coated balloon (Drug-coated balloon, DCB), which is the combined product of traditional balloon angioplasty and advanced drug-eluting technology, is gradually showing its superiority as an effec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M25/10A61M29/02
Inventor 申峰常恩泽袁玲
Owner SHENZHEN SALUBRIS BIOMEDICAL ENG CO LTD