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Novel method for producing Mongolian patent medicine

A technology of Mongolian patent medicine and a new method, applied in the field of Mongolian patent medicine processing, can solve the problems of low bioavailability, slow effect, slow absorption, etc., and achieve the effects of high extraction efficiency, quick effect and simple method

Inactive Publication Date: 2014-02-05
INNER MONGOLIA UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It can solve the shortcomings of slow absorption and low bioavailability of Mongolian medicine powder under the action of stomach, intestines, gastric juice and intestinal juice, slowly releasing active ingredients; and then being absorbed and utilized
[0006] The traditional Mongolian medicine Sanzi Powder has the disadvantages of poor absorption, low bioavailability, and slow effect, whether it is boiled or mixed.

Method used

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  • Novel method for producing Mongolian patent medicine
  • Novel method for producing Mongolian patent medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The production process of extracting Mongolian medicine Sanzi Powder by using artificial gastric juice and artificial intestinal juice as the extraction solvent to obtain the semi-bionic extract of Sanzi Powder is as follows: 10 times the amount of artificial gastric juice (volume of artificial gastric juice L / mass of Sanzi Powder kg); extraction time 30 Minutes; 5 times the amount of artificial intestinal juice (volume L of artificial intestinal juice / mass Kg of Sanzi Powder); extraction time is 50 minutes; the extraction process is completed with stirring at a temperature of 36±1°C. Produced in the following steps:

[0020] 1. Inspection of Sanzi Powder: According to the inspection of Sanzi Powder in the Pharmacopoeia of the People's Republic of China (Part 1 of 2010 Edition), Sanzi Powder meets the requirements.

[0021] 2. Extraction with artificial gastric juice: Put 5kg of Sanzi Powder into an extraction tank, add 50L (volume of artificial gastric juice L / mass of ...

Embodiment 2

[0029] By using artificial gastric juice and artificial intestinal juice as the extraction solvent to extract the Mongolian medicine Sanzi Powder to obtain the semi-bionic extract of Sanzi Powder, the production process is as follows: 10 times the amount of artificial gastric juice (volume of artificial gastric juice L / mass of Sanzi Powder kg); extraction time 45 minutes; 5 times the amount of artificial intestinal juice (volume of artificial intestinal juice L / mass of Sanzi powder kg); extraction time 50 minutes; the extraction process is completed at 36±1°C with temperature-controlled stirring. Produced according to the above steps.

Embodiment 3

[0031] By using artificial gastric juice and artificial intestinal juice as the extraction solvent to extract the Mongolian medicine Sanzi Powder to obtain the semi-bionic extract of Sanzi Powder, the production process is as follows: 10 times the amount of artificial gastric juice (volume of artificial gastric juice L / mass of Sanzi Powder kg); extraction time 60 Minutes; 8 times the amount of artificial intestinal juice (volume of artificial intestinal juice L / mass of Sanzi powder kg); extraction time is 90 minutes; the extraction process is completed at 36±1°C with temperature-controlled stirring. Produced according to the above steps.

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Abstract

The invention discloses a novel method for producing a Mongolian patent medicine. The traditional Sanzi San is prepared by evenly mixing powder of three traditional Chinese medicines including fructus chebulae, fructus gardeniae and fructus meliae toosendan, and mainly used for treating new and old blood heat symptoms, immaturate heat symptoms, extravasate blood and corrected blood mixture, plague heat, gila heat and the like. The traditional Mongolian medicine Sanzi San powder has the defects of being poorly absorbed, low in bioavailability and slow in effect after being boiled or administrated after dissolved. Semi-bionic-process Sanzi San extractant powder can be finally obtained by the following steps: by adopting semi-bionic extraction technology, extracting active substances from the Sanzi San powder respectively by adopting artificial gastric fluid and artificial intestinal fluid, then combining the extraction fluid, and performing reduced pressure concentration and reduced pressure drying. Compared with the traditional Sanzi San, the semi-bionic-process Sanzi San extractant powder has the advantages that the yield of the is improved to 32.94% from 26.47%, the content of geniposide is increased to 5.68% from 4.32, and the bioavailability is improved after the powder is administrated.

Description

technical field [0001] The invention relates to a new processing method of Mongolian patent medicine, in particular to the optimization and control of the technical parameters of the pretreatment of Mongolian medicine Sanzi powder preparation process by semi-bionic extraction technology. Background technique [0002] The Mongolian people have accumulated a lot of medicinal knowledge in the struggle against nature and diseases. For more than 600 years, many classic Mongolian medicine works have been published, and many classic Mongolian medicine prescriptions have been recorded. There are 10 kinds of Mongolian medicine formulations. That is, decoction (boiled), powder, pill, ointment, wine, oil, ash, mixing agent, herbal medicine and gold stone mixture. [0003] As a wonderful work in the treasure house of Chinese medicine, Mongolian medicine has attracted extensive attention from the world's medical circles for its unique theory and curative effect. Before this century, a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/744A61P7/00A61P29/00B01D11/02
CPCY02A50/30
Inventor 田景民陈贵林张久红
Owner INNER MONGOLIA UNIVERSITY
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