Fixing apparatus for volume uniform radiation test of laboratory mice

Abstract

The invention discloses a fixing apparatus for volume uniform radiation test of laboratory mice and belongs to fixing apparatus for animal experiments. The fixing apparatus comprises a cylindrical casing with the bottom end closed and the top end open, a circular cover plate capable of being connected fixedly in a detachable manner and capping the top opening of the cylindrical casing, and multiple water-drop-shaped chambers which are placed in the circular casing for containing the laboratory mice and in the shape fitting with shapes of the laboratory mice. The chambers are in radial arrangement with the centripetal tip ends and outwards round ends, the round ends are tangent with the wall of the casing, and through holes which are designed in size enabling tails of the mice to pass through and run through the wall of the casing and the walls of the chambers are formed below the tangent lines respectively. Multiple laboratory mice can be fixed completely at one time and then subjected to uniform radiation, so that consistency of experimental radiation dose is guaranteed while experiment efficiency is increased. The fixing apparatus is simple in structure, low in cost, convenient to operate and use and easy to produce and promote.

Description

technical field [0001] The invention relates to a radiation fixing device for animal experiments, in particular to a fixing device for uniform radiation experiments in batches of experimental mice. Background technique [0002] Today, due to the gradual application of nuclear technology in the fields of national defense and military, industrial and agricultural production, and medical life sciences, people have more and more opportunities to come into contact with radiation, and the chances of suffering radiation damage also increase accordingly. At the same time, malignant tumors are increasingly becoming the number one killer that threatens human health. With the development of science and technology, radiotherapy technology has also made great progress in recent decades. Therefore, whether it is research and development of anti-radiation drugs with high efficiency, low toxicity and convenient use, or research and improvement of radiation therapy technology for malignant t...

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Problems solved by technology

For example, utility model patent [Fan Saijun, Xu Jiaying, Qin Liqiang, etc. A fixture for rat irradiation experiments. CN201987699U, 2011.09.28. Xu Jiaying, Fan Saijun, Qin Liqiang, etc. A mouse used for radiation experiments Fixing device. CN201977959U, 2011.09.21.] Although multiple mice or rats can be placed side by side into the device for whole-body radiation of experimental animals, since the absorbed dose is inversely proportional to the square of the radiation distance, the distance between the experimental animals and the radiation The uniformity and flatness of the radiation dose received by the source are not ideal

Utility model patent [Liu Yong, Hu Weigang, Xu Qing. A medical mouse tumor irradiation fixation tube and fixation device. CN202283289U, 2012.06.27.] Although 12 mice were irradiated in batches, only the legs of the mice were irradiated. It is impossible for the mice to receive the same radiation dose as the local radiation on the head, and each mouse tube is arranged in a square shape.

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