Hydrogel of composite semipermeable membrane and preparation method thereof

Abstract

The invention relates to a hydrogel of a composite semipermeable membrane and a preparation method thereof. The hydrogel comprises a semipermeable membrane and a hydrogel functional layer, wherein one side of the hydrogel functional layer is attached to the semipermeable membrane; the hydrogel functional layer is prepared from 10-90wt% of hydrophilic polymer material and 90-10wt% of water by adopting any one or combination of more than two of physical crosslinking, chemical crosslinking and radiation crosslinking. The hydrogel material prepared by the method has excellent performances such as high moisture content of the hydrogel and good biocompatibility, also has the characteristics of controlled moisture release rate of the semipermeable membrane; the service time of the hydrogel is prolonged; meanwhile, one side of the semipermeable membrane can be further combined with other accessories such as an adhesive tape, so as to meet more complicated functional requirements.

Description

technical field [0001] The invention relates to a hydrogel of a composite semipermeable membrane and a preparation method thereof. Background technique [0002] Hydrogel materials often need to be combined with some kind of support material to maintain a certain shape and perform specific functions. For example, in the application of medical dressings, hydrogel materials have good biocompatibility, conformability, air permeability and transparency, and the composite support materials also need to have good conformity, breathability and transparency, and reach With a certain anti-peeling strength, such a composite material will not affect the excellent performance of the hydrogel material itself while maintaining a certain shape. Currently common support materials such as sponges, foam materials, non-woven fabrics, etc., have disadvantages such as poor conformability and poor transparency. In contrast, many semi-permeable membrane materials have good conformability, air per...

AI Technical Summary

Problems solved by technology

For example, the Chinese patent application 201110161595.5 published on January 25, 2012 provides a preparation process for wound dressings, which realizes the combination of hydrogel and high-elastic polyurethane film, but because small molecule photoinitiators are added in the preparation process of the dressing , small molecule initiators are often toxic

However, during the polymerization process, this small molecule initiator mostly remains at the end of the polymer or remains in the hydrogel, which has certain safety hazards in clinical application.

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