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Method for increasing content of isoforskolin in coleus medicine

A technology of isoforskine and medicinal materials, which is applied in the field of promoting the synthesis and accumulation of isoforskolin, can solve problems such as low content, and achieve the effects of simple equipment, less investment, and simple and easy implementation process.

Active Publication Date: 2014-04-02
湖北福人药业股份有限公司
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  • Summary
  • Abstract
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  • Claims
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AI Technical Summary

Problems solved by technology

Compared with the wild medicinal materials in Yunnan, the medicinal materials planted in Tongcheng County have no significant difference in pharmacognosy, chemical composition and pharmacology, but the content of the active ingredient isofoscolin is relatively low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Bring the freshly excavated Coleus plants in the base back to the processing workshop, and rinse the surface of the medicinal materials with sediment and other foreign matter. Put it on ultraviolet A for irradiation, the irradiation intensity is 40W, the irradiation time is 12h, the temperature during the irradiation period is 25°C, and the relative humidity is 90%. After irradiation, isofascolin was analyzed by high performance liquid chromatography (HPLC). The results showed that the content of isoforskolin in the roots and rhizomes of Coleus sinensis increased by 33.7% to 94.4% after irradiation.

Embodiment 2

[0017] The experiment was carried out in the same manner as in Example 1, except that ultraviolet B was irradiated, the irradiation intensity was 160W, the irradiation time was 12h, the temperature during irradiation was 24°C, and the relative humidity was 90%. It has been detected that the content of isofascolin in the roots and rhizomes of Coleus sinensis has increased by 20%.

Embodiment 3

[0019] The instrument and irradiation method of ultraviolet irradiation are as follows: fix the ultraviolet lamp tube that can emit ultraviolet A or B on an iron or wooden support, place it about 80cm above the medicinal material, turn on the power, and turn on the ultraviolet lamp.

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Abstract

The invention relates to a method for increasing the content of isoforskolin in the coleus medicine, in particular to a method for promoting isoforskolin to be synthesized and accumulated by inducing the coleus medicine by utilizing ultraviolet light.

Description

technical field [0001] The invention relates to a method for increasing the content of isofeskolin in Coleus sage, in particular to a method for using ultraviolet rays to induce the Coleus sage to promote the synthesis and accumulation of isofaskolin. Background technique [0002] Coleus forskohlii (Coleus forskohlii (Wild.) Briq) is derived from Coleus forskohlii (Wild.) Briq, a plant of the Labiatae family. It is produced in India, Nepal and other countries, as well as my country's Yunnan Huize and Dongchuan. Local folks use it to treat cough, asthma, palpitation, dizziness and other diseases. It has remarkable curative effect and is known as "magic medicine". Modern pharmacological studies have shown that the extract of Coleus sinensis has obvious effects on bronchial asthma, congestive heart failure, and various tumors. Hubei Furen Pharmaceutical Co., Ltd. has developed a new traditional Chinese medicine "Shenzhisu Capsule" with Coleus as the main raw material, and has ...

Claims

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Application Information

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IPC IPC(8): A61K36/53
Inventor 余坤刘焱文叶晓川吴宇星李捷邹鹏程黄婕
Owner 湖北福人药业股份有限公司
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