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Salvia miltiorrhiza and pseudo-ginseng blood-circulation-promoting capsule for treating hemiplegia due to cerebral apoplexy and preparation method of capsule

A technology for cerebral apoplexy and capsules, applied in the field of Danqi Tongmai capsules and preparations for the treatment of cerebral apoplexy and hemiplegia

Inactive Publication Date: 2014-04-16
广西圣特药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The causes of cerebral hemorrhage are firstly hypertension and cerebral arteriosclerosis, and secondly, the onset is usually during labor or emotional agitation. Western medicine is commonly used for treatment, such as 20% mannitol 250ml intravenous infusion, 10~20mg fluoromethexate into the solution Intravenous drip, to blood level, intramuscular injection of 25% magnesium sulfate or oral administration of nifedipine, these drugs can control cerebral edema, reduce intracranial pressure, adjust blood pressure, and relieve symptoms at that time, but they cannot fundamentally solve the caused The cause of cerebral hemorrhage

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0026] (1) Take raw materials by weight:

[0027] Danshen 300g, Astragalus 700g, Dilong 200g, Radix Paeoniae Rubra 200g, Leech 60g, Panax notoginseng 60g;

[0028] (2) Pre-treatment of raw materials: remove impurities from 6 traditional Chinese medicine decoction pieces including salvia miltiorrhiza, astragalus, earthworm, red peony root, leech, and notoginseng, and wash them before feeding. Dry at 60°C~75°C for later use.

[0029] (3) Crushing: take the pre-treated Radix Paeoniae Rubra, leech, and Panax notoginseng and grind them into fine powder, pass through an 80-100 mesh sieve, and sterilize the fine powder at 105°C for 60 minutes, then dry it at 80°C, and set aside;

[0030] (4) Extraction: Take Danshen, Astragalus, and Earthworm, add 65%~75% ethanol with a weight-to-volume ratio of 6~8 times, heat and reflux to extract twice, the first time is 2 hours, the second time is 1 hour, Merge the two reflux extracts, filter, and the filtrate is for subsequent use;

[00...

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Abstract

The invention provides a salvia miltiorrhiza and pseudo-ginseng blood-circulation-promoting capsule for treating hemiplegia due to cerebral apoplexy and a preparation method of the capsule. The capsule is prepared from the following raw materials in parts by weight: 10-35 parts of salvia miltiorrhiza, 9-30 parts of astragalus membranaceus, 5-25 parts of earthworm, 6-25 parts of red peony root, 1-10 parts of leech and 3-15 parts of pseudo-ginseng. The preparation method comprises the following steps: crushing red peony root, leech and pseudo-ginseng, and screening through a screen of 80-100 meshes; adding salvia miltiorrhiza, astragalus membranaceus and earthworm, adding 65-75 percent ethanol the volume of which is 6-8 times of the volume of raw materials; performing heating and reflux filtering twice, 1.5-2.5 hours for the first time and 0.5-1.5 for the second time, combining the two reflux extracts, filtering, and keeping the filtrate for later use; refluxing the extract, putting into a recycling concentrating tank to reclaim ethanol, concentrating to obtain paste with relative density of 1.25-1.35 at 65-75 DEG C, adding fine powder which is crushed red peony root, leech and pseudo-ginseng, uniformly mixing, drying, crushing, screening through a screen of 80-100 meshes, and filling into capsule shells to obtain a capsule medicine. The salvia miltiorrhiza and pseudo-ginseng blood-circulation-promoting capsule has the advantages that a new choice to patients with hemiplegia due to cerebral apoplexy is provided, clinical verification indicates that the salvia miltiorrhiza and pseudo-ginseng blood-circulation-promoting capsule has a remarkable effect on hemiplegia due to cerebral apoplexy.

Description

technical field [0001] The invention relates to a medicine for treating middle division diseases, in particular Danqi Tongmai Capsules for treating cerebral embolism and hemiplegia due to stroke and a preparation method thereof. Background technique [0002] TCM treatment of apoplexy due to syndrome can be traced back to more than two thousand years ago. "Su Wen·Feng Lun" says: "Drinking alcohol and having a stroke means wind leakage. Entering the room and sweating and causing a stroke is internal wind. Newly bathed in a stroke is the first wind." The "stroke" mentioned here does not refer to the name of the disease, but refers to Fengxie's way of feeling evil. "Su Wen·Bazheng Shenming Lun" says: "For righteous and evil people, if the body is exerting force, sweating, the interstitial joints are opened, and when there is a virtual wind, the people among them are also small, so you can't know their feelings, and you can't see their actions." "Qing·Wind Theory" says: "When ...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K9/48A61P9/10A61P25/02A61K35/56A61K35/62
Inventor 刘容在
Owner 广西圣特药业有限公司
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