A traditional Chinese medicine extract with anti-tumor activity and its preparation method and application

Abstract

The invention provides a paliurus ramosissimus extract with excellent anti-tumor activity, as well as a preparation and use thereof. The the major ingredients of the paliurus ramosissimus extract include flavones, terpenes, alkaloids, coumarins, polysaccharides, celluloses, and the glycosides of the flavones, the terpenes, the alkaloids and the coumarins and monomer ingredients thereof. The invention also relates to a preparation method and use of the paliurus ramosissimus extract, and further relates to the uses of pharmaceutical compositions comprising the paliurus ramosissimus extract exclusively and / or as the major active ingredients in preparing anti-tumor medicaments.

Description

technical field [0001] The invention relates to the field of extraction and application of traditional Chinese medicines, in particular to an extract of vegetal vetch with anti-tumor activity and its preparation method and application. Background technique [0002] Tumors, especially malignant tumors, are malignant diseases with extremely high mortality rates, and their treatment is extremely difficult. In the late 20th century, the incidence of tumors has been on the rise for nearly 30 years. At present, the incidence and mortality of cancer in the world have increased by 22% compared with 1990, and will increase by about 50% in the next 20 years. By 2020, the annual number of new cancer patients worldwide will reach 15 million, and 10 million people will die from cancer, most of which will occur in developing countries. The mortality rate caused by tumors in my country accounts for 17.9% of all causes, ranking second, and the incidence rate is on the rise. At present, th...

AI Technical Summary

Problems solved by technology

A large number of long-term clinical evidence shows that although western medicine and western medicine are effective in treating tumors, they have relatively large side effects.

Surgery is suitable for early and mid-term treatment of some local tumors, but most patients cannot prevent tumor recurrence and metastasis by surgical treatment

Although radiotherapy and chemotherapy have a high cure rate, they often cause toxic and side effects such as bone marrow suppression and immunocompromise, making it difficult for patients to adhere to treatment

Moreover, the drug resistance of chemotherapy drugs in the course of treatment has also become one of the difficult problems in current clinical treatment.

Moreover, the problems brought about by various treatment methods and the decline in the quality of life of patients have made how to protect the functions of the body and various organs and improve the quality of life of patients has become a subject of widespread attention.

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