Traditional Chinese medicine extractive having bidirectional immunity adjustment effect and application

A technology of regulating effect and two-way immunity, which is applied in the field of the extract and its preparations of Majiazi, and the preparation of drugs for low immune function and autoimmune diseases, which can solve the problems of narrow safety window, toxic and side effects, etc.

Active Publication Date: 2014-04-23
四川梓橦宫药业股份有限公司
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  • Abstract
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AI Technical Summary

Problems solved by technology

These drugs usually have significant toxi

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0014] The present invention will be further described in detail below in conjunction with examples, but the embodiments of the present invention are not limited thereto.

[0015] One, the preparation method of the seed extract

[0016] 1. Preparation of whole plant ethanol extract

[0017] Take 1kg of the whole plant of S. japonica, add 8 times the amount of 95% ethanol to soak for 1 day, then crush it, add 10 times the amount of 95% ethanol to soak for 2 days to extract, collect the extract, and recover the ethanol under reduced pressure at 50°C until it is free of alcohol Taste, dried to obtain the ethanol extract of the seedlings.

[0018] 2. Preparation of stem and leaf ethanol, petroleum ether and ethyl acetate extracts

[0019] Take 1kg of the stem and leaf of Scutellaria chinensis, add 10 times the amount of 95% ethanol to soak for 1 day, then crush it, then add 10 times the amount of 95% ethanol for reflux extraction, collect the extract, and recover the ethanol un...

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Abstract

The invention discloses a paliurus ramosissimus extractive having the bidirectional immunity adjustment effect and application thereof as a medicine for treating immune function abnormalities. The traditional Chinese medicine extractive disclosed by the invention is a methanol, ethanol, ethyl acetate, petroleum ether or similar solvent extract of paliurus ramosissimus leaves, paliurus ramosissimus roots, paliurus ramosissimus stem leaves or paliurus ramosissimus whole plant and mainly contains terpenes, flavonoids, alkaloids, coumarins (including glycosides and monomers of the above substances), polysaccharides, cellulose and the like; the preparation of the traditional Chinese medicine extractive include tablets, capsules, emplastrums, granules, injections, suppositories, ointments, gels, plastics, linimentums, lotions and sprays. The paliurus ramosissimus extractive and the preparation thereof disclosed by the invention have the bidirectional immunity adjustment effect and can be applied to preparing the medicines for treating immunocompromise and autoimmune diseases.

Description

technical field [0001] The present invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine extract with two-way immunoregulatory effects and its use, specifically the use of the extract and its preparations for preparing medicines for low immune function and autoimmune diseases. Background technique [0002] The immune function of the human body is an important function for the body to resist the invasion of bacteria and viruses, remove damaged, denatured and aging cells in the body, remove metabolic waste in the body, and maintain the stability of the body's internal environment. Immune dysfunction is the initiating factor of many diseases, and it can also occur and aggravate the disease during the course of many diseases. [0003] Immune dysfunction can be divided into primary and secondary types according to different causes. Primary is caused by congenital hypoplasia, most of which are related to genetic...

Claims

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Application Information

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IPC IPC(8): A61K36/72A61P37/04A61P37/02A61P11/00A61P31/18A61P29/00A61P5/16A61P3/10A61P7/04A61P7/06A61P1/04A61P1/16A61P35/00
Inventor 徐超群李东晓袁志翔舒光明阮佳詹雁胡竟一谭镭余悦白筱璐
Owner 四川梓橦宫药业股份有限公司
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